Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase.
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The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis.Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists.Synthesis of GPIb beta with novel transmembrane and cytoplasmic sequences in a Bernard-Soulier patient resulting in GPIb-defective signaling in CHO cells.Molecular genetic analysis of a variant Bernard-Soulier syndrome due to compound heterozygosity for two novel glycoprotein Ibbeta mutations.Proteolysis of platelet receptors in humans and other species.A novel STAT3 inhibitor negatively modulates platelet activation and aggregationEchicetin coated polystyrene beads: a novel tool to investigate GPIb-specific platelet activation and aggregationc-Myc-mediated genomic instability proceeds via a megakaryocytic endomitosis pathway involving Gp1balphaRole of 14-3-3ζ in platelet glycoprotein Ibα-von Willebrand factor interaction-induced signalingPlatelet GPIb-IX-V-dependent signaling.The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activationA functional 14-3-3zeta-independent association of PI3-kinase with glycoprotein Ib alpha, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complexSrc family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway.Platelet integrins and immunoreceptors.Identification of FcgammaRIIa as the ITAM-bearing receptor mediating alphaIIbbeta3 outside-in integrin signaling in human plateletsPlatelet-derived ERp57 mediates platelet incorporation into a growing thrombus by regulation of the αIIbβ3 integrin.Platelet physiology and antiplatelet agents.Src family kinases: at the forefront of platelet activationOf von Willebrand factor and platelets.Impaired alpha(IIb)beta(3) integrin activation and shear-dependent thrombus formation in mice lacking phospholipase D1.Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites.The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation.Prolonged platelet preservation by transient metabolic suppression.Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner.Modularity of the oncoprotein-like properties of platelet glycoprotein Ibalpha.GPIbalpha-selective activation of platelets induces platelet signaling events comparable to GPVI activation events.Signaling role for phospholipase C gamma 2 in platelet glycoprotein Ib alpha calcium flux and cytoskeletal reorganization. Involvement of a pathway distinct from FcR gamma chain and Fc gamma RIIA.GPIb potentiates GPVI-induced responses in human platelets.14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling.A role for glycosphingolipid-enriched microdomains in platelet glycoprotein Ib-mediated platelet activation.
P2860
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P2860
Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase.
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Interaction between von Willeb ...... of phosphoinositide 3-kinase.
@ast
Interaction between von Willeb ...... of phosphoinositide 3-kinase.
@en
type
label
Interaction between von Willeb ...... of phosphoinositide 3-kinase.
@ast
Interaction between von Willeb ...... of phosphoinositide 3-kinase.
@en
prefLabel
Interaction between von Willeb ...... of phosphoinositide 3-kinase.
@ast
Interaction between von Willeb ...... of phosphoinositide 3-kinase.
@en
P2093
P1433
P1476
Interaction between von Willeb ...... of phosphoinositide 3-kinase.
@en
P2093
Kaneo Satoh
Michael C Berndt
Naoki Asazuma
Toshiro Takafuta
Yukio Ozaki
Yutaka Yatomi
P304
P356
10.1182/BLOOD-2002-03-0806
P407
P577
2002-08-29T00:00:00Z