Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

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http://www.wikidata.org/entity/Q30175312

Q30175312

about

Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C Novel modular domain PB1 recognizes PC motif to mediate functional protein-protein interactions NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide Induction of colonic epithelial cell apoptosis by p47-dependent oxidants Identification of an actin-binding site in p47phox an organizer protein of NADPH oxidase Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phox A p21-activated kinase-controlled metabolic switch up-regulates phagocyte NADPH oxidase Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction Phosphorylation of Noxo1 at threonine 341 regulates its interaction with Noxa1 and the superoxide-producing activity of Nox1 Effects of p47phox C terminus phosphorylations on binding interactions with p40phox and p67phox. Structural and functional comparison of p40phox and p67phox SH3 domains Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system New insights into the regulation of neutrophil NADPH oxidase activity in the phagosome: a focus on the role of lipid and Ca(2+) signaling Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells Basic fibroblast growth factor stimulates activation of Rac1 through a p85 betaPIX phosphorylation-dependent pathway Architecture of the p40-p47-p67phox complex in the resting state of the NADPH oxidase. A central role for p67phox Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species Activation and assembly of the NADPH oxidase: a structural perspective Cloning of rat p47phox and comparison with human p47phox The involvement of aldosterone in cyclic stretch-mediated activation of NADPH oxidase in vascular smooth muscle cells Two novel proteins activate superoxide generation by the NADPH oxidase NOX1 Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation Airway smooth muscle relaxation is impaired in mice lacking the p47phox subunit of NAD(P)H oxidase p47phox molecular activation for assembly of the neutrophil NADPH oxidase complex.Regulation of NOXO1 activity through reversible interactions with p22 and NOXA1.p47phox, the phagocyte NADPH oxidase/NOX2 organizer: structure, phosphorylation and implication in diseases Transactivation of Abl by the Crk II adapter protein requires a PNAY sequence in the Crk C-terminal SH3 domain.A molecular mechanism for autoinhibition of the tandem SH3 domains of p47phox, the regulatory subunit of the phagocyte NADPH oxidase.Solution structure of the tandem Src homology 3 domains of p47phox in an autoinhibited form.Properties of phagocyte NADPH oxidase p47-phox mutants with unmasked SH3 (Src homology 3) domains: full reconstitution of oxidase activity in a semi-recombinant cell-free system lacking arachidonic acid p47phox participates in activation of RelA in endothelial cells.The adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase.Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase.Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases.p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.Vascular endothelial growth factor causes translocation of p47phox to membrane ruffles through WAVE1.The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators.Gene transfer and expression in human neutrophils. The phox homology domain of p47phox translocates to the plasma membrane but not to the membrane of mature phagosomes.

P2860

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P2860

Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

Item

http://www.wikidata.org/entity/Q30175312

description

1999 nî lūn-bûn

@nan

1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

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