Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity.
about
Identification and functional analysis of a new phosphorylation site (Y398) in the SH3 domain of Abi-1Induction of colonic epithelial cell apoptosis by p47-dependent oxidantsABL tyrosine kinases: evolution of function, regulation, and specificityAbi-1 forms an epidermal growth factor-inducible complex with Cbl: role in receptor endocytosisNESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylationIdentification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeletonRegulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinaseAllosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferationAbl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinasesCharacterization of a novel member of the DOK family that binds and modulates Abl signalingPhosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replicationType IV secretion in the obligatory intracellular bacterium Anaplasma phagocytophilumThe PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activityc-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activationc-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding proteinThe amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulationRegulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsAn effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machineBcr-Abl induces abnormal cytoskeleton remodeling, beta1 integrin clustering and increased cell adhesion to fibronectin through the Abl interactor 1 pathwayAbelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formationDissecting Nck/Dock signaling pathways in Drosophila visual system.Phosphoregulation of the WAVE regulatory complex and signal integrationDifferential regulation of macropinocytosis by Abi1/Hssh3bp1 isoformsAbelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activationAbl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinaseRegulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptorIdentification of B cell adaptor for PI3-kinase (BCAP) as an Abl interactor 1-regulated substrate of Abl kinasesAbi1 is essential for the formation and activation of a WAVE2 signalling complexUnc119 protects from Shigella infection by inhibiting the Abl family kinasesArg interacts with cortactin to promote adhesion-dependent cell edge protrusionABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memoryReciprocal regulation of Abl kinase by Crk Y251 and Abi1 controls invasive phenotypes in glioblastoma.The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.Intramolecular dynamics within the N-Cap-SH3-SH2 regulatory unit of the c-Abl tyrosine kinase reveal targeting to the cellular membraneC3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesion.Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans.Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functionsTyrosine phosphorylation in the SH3 domain disrupts negative regulatory interactions within the c-Abl kinase core.
P2860
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P2860
Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity.
description
1995 nî lūn-bûn
@nan
1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
name
Abl-interactor-1, a novel SH3 ...... s v-abl transforming activity.
@ast
Abl-interactor-1, a novel SH3 ...... s v-abl transforming activity.
@en
type
label
Abl-interactor-1, a novel SH3 ...... s v-abl transforming activity.
@ast
Abl-interactor-1, a novel SH3 ...... s v-abl transforming activity.
@en
prefLabel
Abl-interactor-1, a novel SH3 ...... s v-abl transforming activity.
@ast
Abl-interactor-1, a novel SH3 ...... s v-abl transforming activity.
@en
P2093
P356
P1433
P1476
Abl-interactor-1, a novel SH3 ...... s v-abl transforming activity.
@en
P2093
P304
P356
10.1101/GAD.9.21.2583
P577
1995-11-01T00:00:00Z