CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure.Inter-individual variation of DNA methylation and its implications for large-scale epigenome mappingPharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesisDNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolutionDNA Methylation Dynamics of Human Hematopoietic Stem Cell DifferentiationMaking sense of big data in health research: Towards an EU action planToward understanding and exploiting tumor heterogeneityArtemisinins Target GABAA Receptor Signaling and Impair α Cell IdentityAnalysing and interpreting DNA methylation data.Comprehensive analysis of DNA methylation data with RnBeads.BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing.DeepBlue epigenomic data server: programmatic data retrieval and analysis of epigenome region setsThe human genomic melting map.CpG island mapping by epigenome prediction.Structural conservation versus functional divergence of maternally expressed microRNAs in the Dlk1/Gtl2 imprinting region.EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic dataWeb-based analysis of (Epi-) genome data using EpiGRAPH and Galaxy.Synergy and competition between cancer genome sequencing and epigenome mapping projects.Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal.Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling.Chromatin accessibility maps of chronic lymphocytic leukaemia identify subtype-specific epigenome signatures and transcription regulatory networks.Somatic mutations of calreticulin in myeloproliferative neoplasms.Genomic distribution and inter-sample variation of non-CpG methylation across human cell types.Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications.A DNA methylation fingerprint of 1628 human samples.Analyzing epigenome data in context of genome evolution and human diseases.Dnmt3a is essential for hematopoietic stem cell differentiation.A reversible gene trap collection empowers haploid genetics in human cells.Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1.Single-cell DNA methylome sequencing and bioinformatic inference of epigenomic cell-state dynamics.Promoter hypermethylation of the phosphatase DUSP22 mediates PKA-dependent TAU phosphorylation and CREB activation in Alzheimer's disease.Pooled CRISPR screening with single-cell transcriptome readout.Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals.DNA methylation signatures link prenatal famine exposure to growth and metabolismHigh-resolution mapping of h1 linker histone variants in embryonic stem cellsReference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.Computational epigenetics.Complex patterns of chromosome 11 aberrations in myeloid malignancies target CBL, MLL, DDB1 and LMO2.Notch inhibition allows oncogene-independent generation of iPS cells
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Principal Investigator and Visiting Professor at the Medical University of Vienna
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Christoph Bock
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Christoph Bock
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Christoph Bock
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Christoph Bock
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Christoph Bock
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Christoph Bock
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Christoph Bock
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Christoph Bock
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Christoph Bock
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Christoph Bock
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Bock C
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Christoph Bock
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Christoph Bock
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Christoph Bock
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Christoph Bock
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Christoph Bock
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Christoph Bock
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