Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
about
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2Identification of a Src kinase SH3 binding site in the C-terminal domain of the human ErbB2 receptor tyrosine kinaseRoles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factorRecombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivationLyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cellsDok-R mediates attenuation of epidermal growth factor-dependent mitogen-activated protein kinase and Akt activation through processive recruitment of c-Src and Csk.SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells.Differential regulation of EphA2 in normal and malignant cellsSrc kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells.Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximabMUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancerThe Transmodulation of HER2 and EGFR by Substance P in Breast Cancer Cells Requires c-Src and Metalloproteinase ActivationEvasion mechanisms to Igf1r inhibition in rhabdomyosarcomaEpidermal growth factor-receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models.Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferationSignal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells.Pathways to tamoxifen resistance.c-Src modulates ErbB2 and ErbB3 heterocomplex formation and function.Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells.Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling.Inhibition of Integrin-HER2 signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppressionPathobiological implications of the d16HER2 splice variant for stemness and aggressiveness of HER2-positive breast cancer.Synergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell linesDHHC20: a human palmitoyl acyltransferase that causes cellular transformationHerceptin conjugates linked by EDC boost direct tumor cell death via programmed tumor cell necrosis.Src inhibitors in the treatment of metastatic bone disease: rationale and clinical dataHuman MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents.p27: a barometer of signaling deregulation and potential predictor of response to targeted therapies.The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesisSmall molecule tyrosine kinase inhibitors: clinical development of anticancer agents.SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatmentFHIT-proteasome degradation caused by mitogenic stimulation of the EGF receptor family in cancer cells.A novel phosphatidic acid-protein-tyrosine phosphatase D2 axis is essential for ERBB2 signaling in mammary epithelial cells.Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition.Update on the molecular profile of the MDA-MB-453 cell line as a model for apocrine breast carcinoma studiesCancer metastasis therapeutic targets and drug discovery: emerging small-molecule protein kinase inhibitors.Loss of Hsp90 association up-regulates Src-dependent ErbB2 activity.Src promotes estrogen-dependent estrogen receptor alpha proteolysis in human breast cancerPhysical Intimacy of Breast Cancer Cells with Mesenchymal Stem Cells Elicits Trastuzumab Resistance through Src Activation
P2860
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P2860
Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
@ast
Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
@en
type
label
Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
@ast
Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
@en
prefLabel
Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
@ast
Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
@en
P2093
P2860
P356
P1433
P1476
Src family kinases and HER2 interactions in human breast cancer cell growth and survival.
@en
P2093
Belsches-Jablonski AP
Biscardi JS
Parsons SJ
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204205
P407
P577
2001-03-01T00:00:00Z
P5875
P6179
1020109614