A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand binding sites
about
The 2006 Automated Function Prediction MeetingDelineation of Polypharmacology across the Human Structural Kinome Using a Functional Site Interaction Fingerprint ApproachModeling enzyme-ligand binding in drug discoveryRaloxifene attenuates Pseudomonas aeruginosa pyocyanin production and virulenceA machine learning-based method to improve docking scoring functions and its application to drug repurposingIn silico elucidation of the molecular mechanism defining the adverse effect of selective estrogen receptor modulatorsPredicting protein ligand binding sites by combining evolutionary sequence conservation and 3D structureA multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homologyDrug discovery using chemical systems biology: identification of the protein-ligand binding network to explain the side effects of CETP inhibitorsDrug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosisFLORA: a novel method to predict protein function from structure in diverse superfamiliesThe Mycobacterium tuberculosis drugome and its polypharmacological implicationsDrug discovery using chemical systems biology: weak inhibition of multiple kinases may contribute to the anti-cancer effect of nelfinavirDrug Promiscuity in PDB: Protein Binding Site Similarity Is KeyTowards structural systems pharmacology to study complex diseases and personalized medicineTuberQ: a Mycobacterium tuberculosis protein druggability databaseProBiS-ligands: a web server for prediction of ligands by examination of protein binding sites.Detecting evolutionary relationships across existing fold space, using sequence order-independent profile-profile alignments.Exploring the structure and function paradigm.SMAP-WS: a parallel web service for structural proteome-wide ligand-binding site comparison.Text mining improves prediction of protein functional sites.Protein pockets: inventory, shape, and comparisonAutomatic prediction of catalytic residues by modeling residue structural neighborhood.Fast dynamics perturbation analysis for prediction of protein functional sites.De-orphaning the structural proteome through reciprocal comparison of evolutionarily important structural featuresPartial order optimum likelihood (POOL): maximum likelihood prediction of protein active site residues using 3D Structure and sequence propertiesFpocket: an open source platform for ligand pocket detection.Local alignment tool based on Hadoop framework and GPU architecturePrediction of ligand-binding sites of proteins by molecular docking calculation for a random ligand libraryInsights into the binding mode of MEK type-III inhibitors. A step towards discovering and designing allosteric kinase inhibitors across the human kinomeDetermining Cysteines Available for Covalent Inhibition Across the Human Kinome.Molecular mechanisms involved in the side effects of fatty acid amide hydrolase inhibitors: a structural phenomics approach to proteome-wide cellular off-target deconvolution and disease association.Opal web services for biomedical applications.Prediction of functionally important residues in globular proteins from unusual central distances of amino acids.High-performance prediction of functional residues in proteins with machine learning and computed input features.Drug repositioning through incomplete bi-cliques in an integrated drug-target-disease network.Protein surface matching by combining local and global geometric information.Skin injury model classification based on shape vector analysisEvolutionary approach to predicting the binding site residues of a protein from its primary sequenceMultiscale modeling of the causal functional roles of nsSNPs in a genome-wide association study: application to hypoxia.
P2860
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P2860
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand binding sites
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A robust and efficient algorit ...... redicting ligand binding sites
@ast
A robust and efficient algorit ...... redicting ligand binding sites
@en
type
label
A robust and efficient algorit ...... redicting ligand binding sites
@ast
A robust and efficient algorit ...... redicting ligand binding sites
@en
prefLabel
A robust and efficient algorit ...... redicting ligand binding sites
@ast
A robust and efficient algorit ...... redicting ligand binding sites
@en
P2860
P1433
P1476
A robust and efficient algorit ...... redicting ligand binding sites
@en
P2860
P2888
P356
10.1186/1471-2105-8-S4-S9
P478
P577
2007-05-22T00:00:00Z
P5875
P6179
1053523249