about
Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and in Vivo Activity.Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ.Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles.Structure-Activity Relationship Studies and Molecular Modeling of Naphthalene-Based Sphingosine Kinase 2 Inhibitors.Structure-activity relationship studies of the lipophilic tail region of sphingosine kinase 2 inhibitors.Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.FTY720 Attenuates Angiotensin II-Induced Podocyte Damage via Inhibiting Inflammatory Cytokines.Inhibition of the SphK1/S1P signaling pathway by melatonin in mice with liver fibrosis and human hepatic stellate cells.Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies.Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism.RNAi screen reveals a role of SPHK2 in dengue virus-mediated apoptosis in hepatic cell lines.Sphingolipids and their metabolism in physiology and disease.A Phase I Study of ABC294640, a First-in-Class Sphingosine Kinase-2 Inhibitor, in Patients with Advanced Solid Tumors.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Drugging sphingosine kinases.
@ast
Drugging sphingosine kinases.
@en
type
label
Drugging sphingosine kinases.
@ast
Drugging sphingosine kinases.
@en
prefLabel
Drugging sphingosine kinases.
@ast
Drugging sphingosine kinases.
@en
P2860
P921
P356
P1433
P1476
Drugging sphingosine kinases.
@en
P2093
Kevin R Lynch
P2860
P304
P356
10.1021/CB5008426
P577
2014-11-19T00:00:00Z
2015-01-16T00:00:00Z