SDM--a server for predicting effects of mutations on protein stability and malfunction.
about
NMNAT1 mutations cause Leber congenital amaurosisCurrent strategies for mutation detection in phenotype-driven screens utilising next generation sequencingMolecular mechanisms of disease-causing missense mutationsPolymorphic cytochrome P450 enzymes (CYPs) and their role in personalized therapyEssential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosisStructure-function analyses of the human SIX1–EYA2 complex reveal insights into metastasis and BOR syndromeStructural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP BindingStructural Insights into the Role of Domain Flexibility in Human DNA Ligase IVUtility of Synechocystis sp. PCC 6803 glutaredoxin A as a platform to study high-resolution mutagenesis of proteinsActivating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.The genomic signature of dog domestication reveals adaptation to a starch-rich dietMutations in GTP binding protein Obg of Mycoplasma synoviae vaccine strain MS-H: implications in temperature-sensitivity phenotypeA sialoreceptor binding motif in the Mycoplasma synoviae adhesin VlhAIdentification of an Allosteric Binding Site on Human Lysosomal Alpha-Galactosidase Opens the Way to New Pharmacological Chaperones for Fabry DiseaseIn vivo protein interaction network analysis reveals porin-localized antibiotic inactivation in Acinetobacter baumannii strain AB5075MECR Mutations Cause Childhood-Onset Dystonia and Optic Atrophy, a Mitochondrial Fatty Acid Synthesis DisorderEffects of Non-Natural Amino Acid Incorporation into the Enzyme Core Region on Enzyme Structure and Function.Modulation of protein stability and aggregation properties by surface charge engineering.Amino acid changes in disease-associated variants differ radically from variants observed in the 1000 genomes project dataset.An association-adjusted consensus deleterious scheme to classify homozygous Mis-sense mutations for personal genome interpretationSDS, a structural disruption score for assessment of missense variant deleteriousness.Platinum: a database of experimentally measured effects of mutations on structurally defined protein-ligand complexes.INPS: predicting the impact of non-synonymous variations on protein stability from sequence.In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity.A Novel Mutation in a Critical Region for the Methyl Donor Binding in DNMT3B Causes Immunodeficiency, Centromeric Instability, and Facial Anomalies Syndrome (ICF).Correlating disease-related mutations to their effect on protein stability: a large-scale analysis of the human proteome.The MULTICOM toolbox for protein structure predictionUsing rigidity analysis to probe mutation-induced structural changes in proteins.MAESTRO--multi agent stability prediction upon point mutations.The role of balanced training and testing data sets for binary classifiers in bioinformatics.Novel compound heterozygous MYO7A mutations in Moroccan families with autosomal recessive non-syndromic hearing lossMycobacterium tuberculosis Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Functions as a Receptor for Human Lactoferrin.Clinical characteristics of patients with central nervous system relapse in BCR-ABL1-positive acute lymphoblastic leukemia: the importance of characterizing ABL1 mutations in cerebrospinal fluidComputational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnosticsOn the effect of protein conformation diversity in discriminating among neutral and disease related single amino acid substitutions.Chaperone Nap1 shields histone surfaces used in a nucleosome and can put H2A-H2B in an unconventional tetrameric form.Cold adaptation, ca2+ dependency and autolytic stability are related features in a highly active cold-adapted trypsin resistant to autoproteolysis engineered for biotechnological applications.The role of the interactome in the maintenance of deleterious variability in human populationsA conservation and rigidity based method for detecting critical protein residues.Computer-Aided Protein Directed Evolution: a Review of Web Servers, Databases and other Computational Tools for Protein Engineering
P2860
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P2860
SDM--a server for predicting effects of mutations on protein stability and malfunction.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
SDM--a server for predicting effects of mutations on protein stability and malfunction.
@ast
SDM--a server for predicting effects of mutations on protein stability and malfunction.
@en
type
label
SDM--a server for predicting effects of mutations on protein stability and malfunction.
@ast
SDM--a server for predicting effects of mutations on protein stability and malfunction.
@en
prefLabel
SDM--a server for predicting effects of mutations on protein stability and malfunction.
@ast
SDM--a server for predicting effects of mutations on protein stability and malfunction.
@en
P2860
P50
P356
P1476
SDM--a server for predicting effects of mutations on protein stability and malfunction.
@en
P2860
P304
P356
10.1093/NAR/GKR363
P407
P433
Web Server issue
P577
2011-05-18T00:00:00Z