In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity.
about
Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosisThe Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.Beyond DNA: An Integrated and Functional Approach for Classifying Germline Variants in Breast Cancer GenesThe Presence, Persistence and Functional Properties of Plasmodium vivax Duffy Binding Protein II Antibodies Are Influenced by HLA Class II Allelic VariantsVariation in Human Cytochrome P-450 Drug-Metabolism Genes: A Gateway to the Understanding of Plasmodium vivax RelapsesmCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistanceMycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance.PinSnps: structural and functional analysis of SNPs in the context of protein interaction networksmCSM-NA: predicting the effects of mutations on protein-nucleic acids interactions.SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity.Arpeggio: A Web Server for Calculating and Visualising Interatomic Interactions in Protein StructuresGenomes, structural biology and drug discovery: combating the impacts of mutations in genetic disease and antibiotic resistance.SDM: a server for predicting effects of mutations on protein stability.Combating mutations in genetic disease and drug resistance: understanding molecular mechanisms to guide drug design.mCSM-AB: a web server for predicting antibody-antigen affinity changes upon mutation with graph-based signaturesFamilial STAG2 germline mutation defines a new human cohesinopathy.Tumour risks and genotype-phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD.Prediction and interpretation of deleterious coding variants in terms of protein structural stability.Analysis of a Novel pncA Mutation for Susceptibility to Pyrazinamide Therapy.Evolution of carbapenem resistance in Acinetobacter baumannii during a prolonged infection.Kinact: a computational approach for predicting activating missense mutations in protein kinases.Tumour risks and genotype–phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD.Modeling transcriptional activation changes to Gal4 variants via structure-based computational mutagenesis.DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability.Structural and Biochemical Insights into the Function and Evolution of SulfoquinovosidasesUnderstanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosisFrequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam
P2860
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P2860
In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity.
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
In silico functional dissectio ...... ty, interactions and activity.
@ast
In silico functional dissectio ...... ty, interactions and activity.
@en
type
label
In silico functional dissectio ...... ty, interactions and activity.
@ast
In silico functional dissectio ...... ty, interactions and activity.
@en
prefLabel
In silico functional dissectio ...... ty, interactions and activity.
@ast
In silico functional dissectio ...... ty, interactions and activity.
@en
P2860
P50
P356
P1433
P1476
In silico functional dissectio ...... ity, interactions and activity
@en
P2093
P2860
P2888
P356
10.1038/SREP19848
P407
P577
2016-01-22T00:00:00Z
P5875
P6179
1037074439