Accelerated leukemogenesis by truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1
about
Molecular Basis and Targeted Inhibition of CBFβ-SMMHC Acute Myeloid Leukemia.Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBFβ interactionMEIS1 regulates an HLF-oxidative stress axis in MLL-fusion gene leukemia.Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice.HDAC8 Inhibition Specifically Targets Inv(16) Acute Myeloid Leukemic Stem Cells by Restoring p53 AcetylationThe C-terminus of CBFβ-SMMHC is required to induce embryonic hematopoietic defects and leukemogenesisRegain control of p53: Targeting leukemia stem cells by isoform-specific HDAC inhibitionTranscription factor RUNX1 promotes survival of acute myeloid leukemia cellsTargeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia.Molecular pathogenesis of core binding factor leukemia: current knowledge and future prospects.Posttranslational modifications of RUNX1 as potential anticancer targets.Mouse models for core binding factor leukemia.Covalent Modifications of RUNX Proteins: Structure Affects Function.Genetic regulation of the RUNX transcription factor family has antitumor effectsDifferential requirements for HIV-1 Vif-mediated APOBEC3G degradation and RUNX1-mediated transcription by core binding factor beta.RUNX1 and CBFβ Mutations and Activities of Their Wild-Type Alleles in AML.RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells.Preleukemia and Leukemia-Initiating Cell Activity in inv(16) Acute Myeloid Leukemia.Genetic compensation of RUNX family transcription factors in leukemia
P2860
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P2860
Accelerated leukemogenesis by truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Accelerated leukemogenesis by ...... gh-affinity binding with RUNX1
@ast
Accelerated leukemogenesis by ...... gh-affinity binding with RUNX1
@en
type
label
Accelerated leukemogenesis by ...... gh-affinity binding with RUNX1
@ast
Accelerated leukemogenesis by ...... gh-affinity binding with RUNX1
@en
prefLabel
Accelerated leukemogenesis by ...... gh-affinity binding with RUNX1
@ast
Accelerated leukemogenesis by ...... gh-affinity binding with RUNX1
@en
P2093
P2860
P1433
P1476
Accelerated leukemogenesis by ...... gh-affinity binding with RUNX1
@en
P2093
Gang Huang
James C Mulloy
John Bushweller
Linda Wolff
Lisa Garrett
Mark Wunderlich
P Paul Liu
R Katherine Hyde
Sheila Compton
P2860
P304
P356
10.1016/J.CCR.2010.03.022
P577
2010-05-01T00:00:00Z