Initial structure-activity relationships of lysophosphatidic acid receptor antagonists: discovery of a high-affinity LPA1/LPA3 receptor antagonist.
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P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesisPharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors.Synthesis and biological evaluation of phosphonate derivatives as autotaxin (ATX) inhibitors.Development of a phosphatase-resistant, L-tyrosine derived LPA1/LPA3 dual antagonist.Synthesis and structure-activity relationships of tyrosine-based inhibitors of autotaxin (ATX).International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature.Lysophosphatidic acid (LPA) and angiogenesis.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsVirtual screening, selection and development of a benzindolone structural scaffold for inhibition of lumazine synthaseLysophosphatidic acid signals through multiple receptors in osteoclasts to elevate cytosolic calcium concentration, evoke retraction, and promote cell survival.2D binary QSAR modeling of LPA3 receptor antagonism.Lysophospholipid receptor nomenclature review: IUPHAR Review 8.Improving the hyperpolarization of (31)P nuclei by synthetic design.LPA Stimulates the Phosphorylation of p130Cas via Gαi2 in Ovarian Cancer CellsIdentification of non-lipid LPA3 antagonists by virtual screening.Lysophospholipid interactions with protein targets.Structure-based drug design identifies novel LPA3 antagonists.Lysophosphatidic acid-1-receptor targeting agents for fibrosis.Mechanisms of the lysophosphatidic acid-induced increase in [Ca(2+)](i) in skeletal muscle cells.Role of lysophosphatidic acid in the regulation of uterine leiomyoma cell proliferation by phospholipase D and autotaxin.Lysophosphatidic acid as a mediator for proinflammatory agonists in a human corneal epithelial cell line.Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA
P2860
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P2860
Initial structure-activity relationships of lysophosphatidic acid receptor antagonists: discovery of a high-affinity LPA1/LPA3 receptor antagonist.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Initial structure-activity rel ...... LPA1/LPA3 receptor antagonist.
@ast
Initial structure-activity rel ...... LPA1/LPA3 receptor antagonist.
@en
type
label
Initial structure-activity rel ...... LPA1/LPA3 receptor antagonist.
@ast
Initial structure-activity rel ...... LPA1/LPA3 receptor antagonist.
@en
prefLabel
Initial structure-activity rel ...... LPA1/LPA3 receptor antagonist.
@ast
Initial structure-activity rel ...... LPA1/LPA3 receptor antagonist.
@en
P2093
P1476
Initial structure-activity rel ...... LPA1/LPA3 receptor antagonist.
@en
P2093
Brian H Heasley
Kevin R Lynch
Renata Jarosz
Timothy L Macdonald
P304
P356
10.1016/J.BMCL.2004.03.076
P407
P577
2004-06-01T00:00:00Z