Critical functions for c-Myb at three checkpoints during thymocyte development. - Wikidata - awgldk - TriplyDB

Critical functions for c-Myb at three checkpoints during thymocyte development.

Critical functions for c-Myb at three checkpoints during thymocyte development.

http://www.wikidata.org/entity/Q30433753

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Hypomethylation of WNT5A, CRIP1 and S100P in prostate cancer c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development A B-Myb complex containing clathrin and filamin is required for mitotic spindle function.GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation Fetal globin gene repressors as drug targets for molecular therapies to treat the β-globinopathies MicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and development Transcriptional control of CD4 and CD8 coreceptor expression during T cell development Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis TRAF7 sequesters c-Myb to the cytoplasm by stimulating its sumoylation.Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells Regulation of GATA-3 expression during CD4 lineage differentiation.T-cells null for the MED23 subunit of mediator express decreased levels of KLF2 and inefficiently populate the peripheral lymphoid organs Reduced c-Myb activity compromises HSCs and leads to a myeloproliferation with a novel stem cell basis Myb promotes centriole amplification and later steps of the multiciliogenesis program.miR-150 regulates the development of NK and iNKT cells.c-Myb promotes the survival of CD4+CD8+ double-positive thymocytes through upregulation of Bcl-xL T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo.c-Myb is required for pro-B cell differentiation.The transcription factor c-Myb primes CD4+CD8+ immature thymocytes for selection into the iNKT lineage.The carbonic anhydrase I locus contains a c-Myb target promoter and modulates differentiation of murine erythroleukemia cells.Requirement of c-Myb for p210(BCR/ABL)-dependent transformation of hematopoietic progenitors and leukemogenesis Identification of novel genes and transcription factors involved in spleen, thymus and immunological development and function.c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis.Potential tumor suppressor role for the c-Myb oncogene in luminal breast cancer.p89c-Myb is not required for fetal or adult hematopoiesis The Wnt-NLK signaling pathway inhibits A-Myb activity by inhibiting the association with coactivator CBP and methylating histone H3.The C-MYB story--is it definitive?From the cradle to the grave: activities of GATA-3 throughout T-cell development and differentiation.Transcriptional control of invariant NKT cell development.c-Myb regulates cell cycle-dependent expression of Erbin: an implication for a novel function of Erbin.MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas.An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance.MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development Regulation of the Flt3 Gene in Haematopoietic Stem and Early Progenitor Cells.CD4-CD8 lineage differentiation: Thpok-ing into the nucleus.The enigma of CD4-lineage specification.Alu elements mediate MYB gene tandem duplication in human T-ALL

P2860

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P2860

Critical functions for c-Myb at three checkpoints during thymocyte development.

http://www.wikidata.org/entity/Q30433753

description

2004 nî lūn-bûn

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2004 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2004 թվականի հունիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Critical functions for c-Myb at three checkpoints during thymocyte development.

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Critical functions for c-Myb at three checkpoints during thymocyte development.

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Critical functions for c-Myb at three checkpoints during thymocyte development.

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Critical functions for c-Myb at three checkpoints during thymocyte development.

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prefLabel

Critical functions for c-Myb at three checkpoints during thymocyte development.

@ast

Critical functions for c-Myb at three checkpoints during thymocyte development.

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Nature Immunology

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Critical functions for c-Myb at three checkpoints during thymocyte development.

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P2093

Christopher S Kremer

http://www.w3.org/2001/XMLSchema#string

Manfred Kraus

http://www.w3.org/2001/XMLSchema#string

Timothy P Bender

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P2860

The myb gene family in cell growth, differentiation and apoptosis

Requirement for RORgamma in thymocyte survival and lymphoid organ development

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

c-Myb is essential for early T cell development.

Differentiation of mouse erythroleukemia cells is blocked by late up-regulation of a c-myb transgene.

Differential regulation of c-Myb-induced transcription activation by a phosphorylation site in the negative regulatory domain.

c-Myb binds to a sequence in the proximal region of the RAG-2 promoter and is essential for promoter activity in T-lineage cells.

Pleiotropic changes controlled by the pre-T-cell receptor.

T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination

Bclx regulates the survival of double-positive thymocytes.

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721-729

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10.1038/NI1085

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7

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5

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2004-06-13T00:00:00Z

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15195090

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