Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytes
about
Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approachesCalmodulin-dependent protein kinase II: linking heart failure and arrhythmiasNa+ channel function, regulation, structure, trafficking and sequestrationCa(2+) current facilitation is CaMKII-dependent and has arrhythmogenic consequencesDeterminants in CaV1 Channels That Regulate the Ca2+ Sensitivity of Bound CalmodulinCardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in vivoFRET detection of calmodulin binding to the cardiac RyR2 calcium release channelCalmodulin binding proteins provide domains of local Ca2+ signaling in cardiac myocytesComputational models reduce complexity and accelerate insight into cardiac signaling networksSynergy between CaMKII substrates and β-adrenergic signaling in regulation of cardiac myocyte Ca(2+) handling.Differential integration of Ca2+-calmodulin signal in intact ventricular myocytes at low and high affinity Ca2+-calmodulin targets.Automated analysis of contractile force and Ca2+ transients in engineered heart tissue.Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.Regulation of excitation-contraction coupling in mouse cardiac myocytes: integrative analysis with mathematical modellingOxidized calmodulin kinase II regulates conduction following myocardial infarction: a computational analysis.Models of cardiac excitation-contraction coupling in ventricular myocytesMuscle-type specific autophosphorylation of CaMKII isoforms after paced contractions.Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule densityCalmodulin-controlled spatial decoding of oscillatory Ca2+ signals by calcineurin.Role of CaMKII in RyR leak, EC coupling and action potential duration: a computational model.Recognition of β-calcineurin by the domains of calmodulin: thermodynamic and structural evidence for distinct rolesMultiscale model of dynamic neuromodulation integrating neuropeptide-induced signaling pathway activity with membrane electrophysiology.Integrative modeling of the cardiac ventricular myocyte.Ca²⁺-calmodulin-dependent protein kinase II regulation of cardiac excitation-transcription coupling.Cardiac myocytes and local signaling in nano-domains.Chasing cardiac physiology and pathology down the CaMKII cascadeSpontaneous neurotransmission signals through store-driven Ca(2+) transients to maintain synaptic homeostasisMechanistic Investigation of the Arrhythmogenic Role of Oxidized CaMKII in the HeartComputational analysis of the regulation of Ca(2+) dynamics in rat ventricular myocytesSimulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials.Modeling Local X-ROS and Calcium Signaling in the Heart.Combined in vivo and in silico investigations of activation of glycolysis in contracting skeletal muscleLocalized calcineurin confers Ca2+-dependent inactivation on neuronal L-type Ca2+ channels.Modelling intracellular competition for calcium: kinetic and thermodynamic control of different molecular modes of signal decodingCaMKII-induced shift in modal gating explains L-type Ca(2+) current facilitation: a modeling study.Calcineurin-dependent ion channel regulation in heart.Calcium/calmodulin-dependent kinase II regulation of cardiac ion channels.Modeling CaMKII in cardiac physiology: from molecule to tissue.Cardiac calmodulin kinase: a potential target for drug design.Beta-adrenergic receptor signaling in the heart: role of CaMKII.
P2860
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P2860
Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytes
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Calmodulin mediates differenti ...... local Ca2+ in cardiac myocytes
@ast
Calmodulin mediates differenti ...... local Ca2+ in cardiac myocytes
@en
type
label
Calmodulin mediates differenti ...... local Ca2+ in cardiac myocytes
@ast
Calmodulin mediates differenti ...... local Ca2+ in cardiac myocytes
@en
prefLabel
Calmodulin mediates differenti ...... local Ca2+ in cardiac myocytes
@ast
Calmodulin mediates differenti ...... local Ca2+ in cardiac myocytes
@en
P2860
P1433
P1476
Calmodulin mediates differenti ...... local Ca2+ in cardiac myocytes
@en
P2860
P304
P356
10.1529/BIOPHYSJ.108.128728
P407
P577
2008-08-08T00:00:00Z