SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways. - Wikidata - awgldk - TriplyDB

SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.

SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.

http://www.wikidata.org/entity/Q30440069

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P38MAPK-dependent phosphorylation and degradation of SRC-3/AIB1 and RARalpha-mediated transcription Activation of p53 transcriptional activity by SMRT: a histone deacetylase 3-independent function of a transcriptional corepressor Corepressors: custom tailoring and alterations while you wait.Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2 Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways Thyroid hormone receptors mutated in liver cancer function as distorted antimorphs Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly.The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor Estrogen receptors recruit SMRT and N-CoR corepressors through newly recognized contacts between the corepressor N terminus and the receptor DNA binding domain.NCoR1 mediates papillomavirus E8;E2C transcriptional repression Regulation of SMRT corepressor dimerization and composition by MAP kinase phosphorylation.Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants.Corepressors, nuclear receptors, and epigenetic factors on DNA: a tail of repression.Kinases and protein phosphorylation as regulators of steroid hormone action Regulated clearance of histone deacetylase 3 protects independent formation of nuclear receptor corepressor complexes.Nuclear hormone receptor corepressor promotes esophageal cancer cell invasion by transcriptional repression of interferon-γ-inducible protein 10 in a casein kinase 2-dependent manner.Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein Modulation of the host cell proteome by the intracellular apicomplexan parasite Toxoplasma gondii Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence Emerging roles of the corepressors NCoR1 and SMRT in homeostasis.Cdk2 and Pin1 negatively regulate the transcriptional corepressor SMRT Cell signaling and nuclear receptors: new opportunities for molecular pharmaceuticals in liver disease.CK2-NCoR signaling cascade promotes prostate tumorigenesis Response of SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) corepressors to mitogen-activated protein kinase kinase kinase cascades is determined by alternative mRNA splicing.New insights into the functions and regulation of the transcriptional corepressors SMRT and N-CoR Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs).Thyroid hormone receptor mutations found in renal clear cell carcinomas alter corepressor release and reveal helix 12 as key determinant of corepressor specificity.G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor alpha-mediated transcriptional regulation.S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development.The ability of thyroid hormone receptors to sense t4 as an agonist depends on receptor isoform and on cellular cofactors.Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes.Nuclear receptors outside the nucleus: extranuclear signalling by steroid receptors.Activation of the unliganded estrogen receptor by prolactin in breast cancer cells.Coactivators and corepressors of NF-kappaB in IkappaB alpha gene promoter.Short linear motif acquisition, exon formation and alternative splicing determine a pathway to diversity for NCoR-family co-repressors.TNF-α inhibits aquaporin 5 expression in human salivary gland acinar cells via suppression of histone H4 acetylation.Protein kinase A phosphorylates NCoR to enhance its nuclear translocation and repressive function in human prostate cancer cells.Divergent JNK Phosphorylation of HDAC3 in Triple-Negative Breast Cancer Cells Determines HDAC Inhibitor Binding and Selectivity.Expression of ERβ and its co-regulators p300 and NCoR in human transitional cell bladder cancer.

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P2860

SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.

http://www.wikidata.org/entity/Q30440069

description

2004 nî lūn-bûn

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2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

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2004年論文

@zh-tw

2004年论文

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name

SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.

@ast

SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.

@en

type

label

SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.

@ast

SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.

@en

prefLabel

SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.

@ast

SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.

@en

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Journal of Biological Chemistry

P1476

SMRT and N-CoR corepressors are regulated by distinct kinase signaling pathways.

@en

P2093

Brian A Jonas

http://www.w3.org/2001/XMLSchema#string

Martin L Privalsky

http://www.w3.org/2001/XMLSchema#string

P2860

SMRTe, a silencing mediator for retinoid and thyroid hormone receptors-extended isoform that is more related to the nuclear receptor corepressor

Translating the Histone Code

A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization

The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2

Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.

Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

Arsenic trioxide is a potent inhibitor of the interaction of SMRT corepressor with Its transcription factor partners, including the PML-retinoic acid receptor alpha oncoprotein found in human acute promyelocytic leukemia

Identification of a signal-responsive nuclear export sequence in class II histone deacetylases

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54676-54686

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scholarly article

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10.1074/JBC.M410128200

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P433

52

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P478

279

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P577

2004-10-18T00:00:00Z

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15491994

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2653424

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