A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function.
about
Structural insights into TDP-43 in nucleic-acid binding and domain interactionsRNA-processing protein TDP-43 regulates FOXO-dependent protein quality control in stress responseHistone methylation restrains the expression of subtype-specific genes during terminal neuronal differentiation in Caenorhabditis elegansTDP-43 identified from a genome wide RNAi screen for SOD1 regulatorsMitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degenerationThe acrosomal protein SP-10 (Acrv1) is an ideal marker for staging of the cycle of seminiferous epithelium in the mouse.Germ cell-specific disruption of the Meig1 gene causes impaired spermiogenesis in mice.TDP-43 is a transcriptional repressor: the testis-specific mouse acrv1 gene is a TDP-43 target in vivo.Nuclear scaffold attachment sites within ENCODE regions associate with actively transcribed genes.Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis.Transgenic rat model of neurodegeneration caused by mutation in the TDP gene.Functional cooperation between CREM and GCNF directs gene expression in haploid male germ cellsTAR DNA-binding protein 43 in neurodegenerative disease.Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43.TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor.Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration.TDP-43 potentiates alpha-synuclein toxicity to dopaminergic neurons in transgenic miceReporter mice express green fluorescent protein at initiation of meiosis in spermatocytesA "two-hit" hypothesis for inclusion formation by carboxyl-terminal fragments of TDP-43 protein linked to RNA depletion and impaired microtubule-dependent transport.Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies.Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration.Caenorhabditis elegans RNA-processing protein TDP-1 regulates protein homeostasis and life spanComparison of parallel high-throughput RNA sequencing between knockout of TDP-43 and its overexpression reveals primarily nonreciprocal and nonoverlapping gene expression changes in the central nervous system of DrosophilaTruncation of the TAR DNA-binding protein 43 is not a prerequisite for cytoplasmic relocalization, and is suppressed by caspase inhibition and by introduction of the A90V sequence variantImmunolocalization of TAR DNA-binding protein of 43 kDa (TDP-43) in mouse seminiferous epithelium.TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysisThe truncated C-terminal RNA recognition motif of TDP-43 protein plays a key role in forming proteinaceous aggregates.Misregulated RNA processing in amyotrophic lateral sclerosis.Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 ProteinopathiesFunctional mapping of the interaction between TDP-43 and hnRNP A2 in vivoMutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis.Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases.Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans.TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration.The role of RNA processing in the pathogenesis of motor neuron degeneration.The role of an E-box element: multiple frunctions and interacting partners.Implications of the prion-related Q/N domains in TDP-43 and FUS.TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies.
P2860
Q24647225-F026131A-D623-4C73-A991-FBC29C35ED38Q27312567-E8C1E744-4FFF-4839-A85E-DB54F6F94467Q27318351-048BF843-E89F-4339-8278-84C6BED45A57Q28482611-87C57D97-C9C6-492F-A285-5DC5B1809D03Q28566372-21C47D66-E267-464D-8FFC-139C0AA153B3Q30370721-38876C31-87CE-4168-99BC-7B83CC485CEAQ30411425-65B37084-101F-421E-B934-3121A0A4A485Q30427637-21106E26-2590-4509-BC51-80BAEA043844Q30432919-0F260FC4-0CB3-4C57-B57F-AE352B565386Q30492839-F243144F-2AA8-4A36-940E-F9012C7C0BB3Q30494776-85DC2EDB-4DC3-43A6-9168-7FB1B7EA3B4CQ33548806-9EBF44A8-031D-49D1-9EE0-1F6C46F14983Q33783208-C630778C-8F98-40D7-91EE-DA4DFF28FA1CQ33941040-B271450F-BACC-4419-A23B-624A80D9A63BQ34074385-97CA742B-62FC-45DB-B92C-33A8F46A7F8DQ34155890-363439FC-645E-42E3-BA35-2E291A72ECD4Q34642738-D28D2788-9264-4D4D-A10D-6C796EEF2BBDQ34648581-BECA9E99-B124-4FB1-AFC6-5028427B1985Q34986497-93779FE3-2848-45F0-93FE-64FE7BF938D7Q34998181-3FF796E0-1A58-402C-9692-26003567FBA7Q35092787-A588FCB3-4360-4457-88F1-EF01786C9449Q35773678-90AEDF7D-572C-4599-ACED-508F9B92CC65Q35868223-223A95F4-42BC-478D-BED6-047835761953Q36065980-0760FB24-8136-41AC-9847-719560D24763Q36373142-652801F9-C0E7-4338-8339-DF52445A281DQ36397371-BFAA4742-504F-4F9F-BCC4-863786973561Q36536399-6045F208-F5CB-4F5A-8449-1395E02CF47CQ36724968-F0A611E4-232B-442C-9B90-EB8530845535Q36999634-1D3925AB-2D20-4A0E-A6F4-AC7E3FEF70CFQ37136781-95456747-306A-405E-B311-DC8E501C1EBDQ37259106-B593FF33-8E84-42D0-9AA9-09B9A9B69F6EQ37379471-6380442A-F93D-4AA4-BBD5-A0B513B3C9E7Q37409270-4C10D6B2-CDC8-4D8D-A53B-716557EA9BB3Q37691547-67698028-7C49-4D21-8811-9BCB7634E94EQ37733168-EDC8B748-1515-4790-A98B-B09822B86EB3Q37774045-5A03C164-9072-4BCF-8ADC-4187390E7C4BQ37785442-606A17A8-E43A-4431-B71E-9AAB404A9FB7Q37816817-B2618CFE-D7DC-4AB9-AA1E-9A4782B9DA17Q37903412-8FF2A8BE-D6C5-4CF8-97C1-376B827CF9AEQ37904288-947A83C8-3ED9-4C2A-9608-A9D728E0DDFB
P2860
A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A novel CpG-free vertebrate in ...... TDP-43 in insulator function.
@ast
A novel CpG-free vertebrate in ...... TDP-43 in insulator function.
@en
type
label
A novel CpG-free vertebrate in ...... TDP-43 in insulator function.
@ast
A novel CpG-free vertebrate in ...... TDP-43 in insulator function.
@en
prefLabel
A novel CpG-free vertebrate in ...... TDP-43 in insulator function.
@ast
A novel CpG-free vertebrate in ...... TDP-43 in insulator function.
@en
P2093
P2860
P356
P1476
A novel CpG-free vertebrate in ...... TDP-43 in insulator function.
@en
P2093
Craig Urekar
Mayuresh M Abhyankar
Prabhakara P Reddi
P2860
P304
36143-36154
P356
10.1074/JBC.M705811200
P407
P577
2007-10-11T00:00:00Z