The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure.

The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure.

Item
http://www.wikidata.org/entity/Q30450420
Activation of a mammalian origin of replication by chromosomal rearrangement.Multiple origins of replication in the dihydrofolate reductase amplicons of a methotrexate-resistant chinese hamster cell line.Identification and characterization of a gene that is coamplified with dihydrofolate reductase in a methotrexate-resistant CHO cell lineMatrix attachment regions are positioned near replication initiation sites, genes, and an interamplicon junction in the amplified dihydrofolate reductase domain of Chinese hamster ovary cells.Amplification of the ribonucleotide reductase small subunit gene: analysis of novel joints and the mechanism of gene duplication in vaccinia virusNovel DNA sequences at chromosome 10q26 are amplified in human gastric carcinoma cell lines: molecular cloning by competitive DNA reassociationA highly amplified mouse gene is homologous to the human interferon-responsive Sp100 gene encoding an autoantigen associated with nuclear dots.Demethylation enhances removal of pyrimidine dimers from the overall genome and from specific DNA sequences in Chinese hamster ovary cellsStructure of a palindromic amplicon junction implicates microhomology-mediated end joining as a mechanism of sister chromatid fusion during gene amplification.An amplified mosquito dihydrofolate reductase gene: amplicon size and chromosomal distribution.The Chinese hamster dihydrofolate reductase replication origin decision point follows activation of transcription and suppresses initiation of replication within transcription units.
P2860

The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure.

Item
http://www.wikidata.org/entity/Q30450420
description
1988 nî lūn-bûn
@nan
1988 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
The dihydrofolate reductase am ...... markably uniform in structure.
@ast
The dihydrofolate reductase am ...... markably uniform in structure.
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type
label
The dihydrofolate reductase am ...... markably uniform in structure.
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The dihydrofolate reductase am ...... markably uniform in structure.
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The dihydrofolate reductase am ...... markably uniform in structure.
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The dihydrofolate reductase am ...... markably uniform in structure.
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P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
The dihydrofolate reductase am ...... markably uniform in structure.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932