Organization and genesis of dihydrofolate reductase amplicons in the genome of a methotrexate-resistant Chinese hamster ovary cell line.
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P1343
Inverted repeats as genetic elements for promoting DNA inverted duplication: implications in gene amplificationInitiation of replication in the Chinese hamster dihydrofolate reductase domain.Activation of a mammalian origin of replication by chromosomal rearrangement.Radiation effects on DNA synthesis in a defined chromosomal replicon.Multiple origins of replication in the dihydrofolate reductase amplicons of a methotrexate-resistant chinese hamster cell line.Identification and characterization of a gene that is coamplified with dihydrofolate reductase in a methotrexate-resistant CHO cell lineReplication in the amplified dihydrofolate reductase domain in CHO cells may initiate at two distinct sites, one of which is a repetitive sequence element.High-resolution mapping of replication fork movement through the amplified dihydrofolate reductase domain in CHO cells by in-gel renaturation analysis.Matrix attachment regions are positioned near replication initiation sites, genes, and an interamplicon junction in the amplified dihydrofolate reductase domain of Chinese hamster ovary cells.The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure.Bacterial artificial chromosome library for genome-wide analysis of Chinese hamster ovary cells.Origin-dependent inverted-repeat amplification: a replication-based model for generating palindromic amplicons.Co-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplificationAmplification of the ribonucleotide reductase small subunit gene: analysis of novel joints and the mechanism of gene duplication in vaccinia virusNovel DNA sequences at chromosome 10q26 are amplified in human gastric carcinoma cell lines: molecular cloning by competitive DNA reassociationInduction of circles of heterogeneous sizes in carcinogen-treated cells: two-dimensional gel analysis of circular DNA molecules.Unstable amplification of two extrachromosomal elements in alpha-difluoromethylornithine-resistant Leishmania donovani.Amplification of the multidrug resistance gene pfmdr1 in Plasmodium falciparum has arisen as multiple independent eventsEvolution and stability of chromosomal DNA coamplified with the CAD geneMolecular structure and evolution of double-minute chromosomes in methotrexate-resistant cultured mouse cellsAn intramolecular recombination mechanism for the formation of the rRNA gene palindrome of Tetrahymena thermophila.Widespread and nonrandom distribution of DNA palindromes in cancer cells provides a structural platform for subsequent gene amplification.Molecular biology of double-minute chromosomes.Amplified inverted duplications within and adjacent to heterologous selectable DNA.Structure of a palindromic amplicon junction implicates microhomology-mediated end joining as a mechanism of sister chromatid fusion during gene amplification.Transposition of human immunoglobulin V kappa genes within the same chromosome and the mechanism of their amplification.An amplified mosquito dihydrofolate reductase gene: amplicon size and chromosomal distribution.Hairpin structures are the primary amplification products: a novel mechanism for generation of inverted repeats during gene amplification.Structure of four amplified DNA novel joints.
P2860
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P2860
Organization and genesis of dihydrofolate reductase amplicons in the genome of a methotrexate-resistant Chinese hamster ovary cell line.
description
1988 nî lūn-bûn
@nan
1988 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Organization and genesis of di ...... inese hamster ovary cell line.
@ast
Organization and genesis of di ...... inese hamster ovary cell line.
@en
type
label
Organization and genesis of di ...... inese hamster ovary cell line.
@ast
Organization and genesis of di ...... inese hamster ovary cell line.
@en
prefLabel
Organization and genesis of di ...... inese hamster ovary cell line.
@ast
Organization and genesis of di ...... inese hamster ovary cell line.
@en
P2093
P2860
P356
P1476
Organization and genesis of di ...... inese hamster ovary cell line.
@en
P2093
P2860
P304
P356
10.1128/MCB.8.6.2316
P407
P4510
P577
1988-06-01T00:00:00Z