about
A general two-metal-ion mechanism for catalytic RNACircular RNAs: relics of precellular evolution?RNA and transcriptional modulation of gene expressionRetroviral insertions in the murine His-1 locus activate the expression of a novel RNA that lacks an extensive open reading frameBefore enzymes and templates: theory of surface metabolismIn vitro selection, characterization, and application of deoxyribozymes that cleave RNAPMC113127X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid.CBP2 protein promotes in vitro excision of a yeast mitochondrial group I intron.Combinatorial screening and intracellular antiviral activity of hairpin ribozymes directed against hepatitis B virus.Chloroplast ribosomal intron of Chlamydomonas reinhardtii: in vitro self-splicing, DNA endonuclease activity and in vivo mobilityDirect measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena.A conserved base pair within helix P4 of the Tetrahymena ribozyme helps to form the tertiary structure required for self-splicingThe conserved U.G pair in the 5' splice site duplex of a group I intron is required in the first but not the second step of self-splicing.Three-dimensional model of the active site of the self-splicing rRNA precursor of TetrahymenaStructural conventions for group I intronsKinetics of bulge bases in small RNAs and the effect of pressure on itStereoselective arginine binding is a phylogenetically conserved property of group I self-splicing RNAs.Cocrystal structure of an editing complex of Klenow fragment with DNASite-selective cleavage of structured RNA by a staphylococcal nuclease-DNA hybrid.Site-specific deoxynucleotide substitutions in yeast U6 snRNA block splicing of pre-mRNA in vitro.Transposase makes critical contacts with, and is stimulated by, single-stranded DNA at the P element termini in vitro.Genetics first or metabolism first? The formamide clue.Life and death of a cardiac myocyte: principles of cellular biology.RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron.Current status of ribozymes as gene therapy agents for cancer.RNA catalyses nuclear pre-mRNA splicingExperimental and emerging therapies for chronic hepatitis C virus infection.A new 2'-hydroxyl protecting group for the automated synthesis of oligoribonucleotidesFormation of sheared G:A base pairs in an RNA duplex modelled after ribozymes, as revealed by NMR.Self-cleavage activity of the genomic HDV ribozyme in the presence of various divalent metal ions.NMR studies of G:A mismatches in oligodeoxyribonucleotide duplexes modelled after ribozymesRibozymes that cleave reovirus genome segment S1 also protect cells from pathogenesis caused by reovirus infectionThe RNA-protein complex: direct probing of the interfacial recognition dynamics and its correlation with biological functions.In vitro selection of deoxyribozymes active with Cd(2+) ions resulting in variants of DNAzyme 8-17.Inhibition of fatty acid synthesis by expression of an acetyl-CoA carboxylase-specific ribozyme geneChemical synthesis of biologically active oligoribonucleotides using beta-cyanoethyl protected ribonucleoside phosphoramidites.Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication--potential effectiveness against most presently sequenced HIV-1 isolates.A phosphorothioate at the 3' splice-site inhibits the second splicing step in a group I intron.Two guanosine binding sites exist in group I self-splicing IVS RNAs.
P2860
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P2860
description
1987 nî lūn-bûn
@nan
1987 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
The chemistry of self-splicing RNA and RNA enzymes.
@ast
The chemistry of self-splicing RNA and RNA enzymes.
@en
type
label
The chemistry of self-splicing RNA and RNA enzymes.
@ast
The chemistry of self-splicing RNA and RNA enzymes.
@en
prefLabel
The chemistry of self-splicing RNA and RNA enzymes.
@ast
The chemistry of self-splicing RNA and RNA enzymes.
@en
P356
P1433
P1476
The chemistry of self-splicing RNA and RNA enzymes.
@en
P2093
P304
P356
10.1126/SCIENCE.2438771
P407
P577
1987-06-01T00:00:00Z