Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness - Wikidata - awgldk - TriplyDB

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

http://www.wikidata.org/entity/Q30458185

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Mitochondrial DNA stress primes the antiviral innate immune response Structure of the essential MTERF4:NSUN4 protein complex reveals how an MTERF protein collaborates to facilitate rRNA modification The rise of mitochondria in medicine Twists in views on RB functions in cellular signaling, metabolism and stem cells The human mitochondrial transcriptome and the RNA-binding proteins that regulate its expression Structural basis for S-adenosylmethionine binding and methyltransferase activity by mitochondrial transcription factor B1 The Role of the Transcription Factor Foxo3 in Hearing Maintenance: Informed Speculation on a New Player in the Cochlea A peep into mitochondrial disorder: multifaceted from mitochondrial DNA mutations to nuclear gene modulation Emerging links between E2F control and mitochondrial function Mitochondrial regulation of β-cell function: maintaining the momentum for insulin release Mitochondrial ribosomal RNA (rRNA) methyltransferase family members are positioned to modify nascent rRNA in foci near the mitochondrial DNA nucleoid Transcription-independent role for human mitochondrial RNA polymerase in mitochondrial ribosome biogenesis Cisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functions ROS function in redox signaling and oxidative stress Characterization of the Transcriptomes of Lgr5+ Hair Cell Progenitors and Lgr5- Supporting Cells in the Mouse Cochlea.Overexpression of the mitochondrial methyltransferase TFB1M in the mouse does not impact mitoribosomal methylation status or hearing.A deafness-associated tRNAHis mutation alters the mitochondrial function, ROS production and membrane potential.Time course of cell death due to acoustic overstimulation in the mouse medial geniculate body and primary auditory cortex Oxidative stress diverts tRNA synthetase to nucleus for protection against DNA damage E2F transcription factor 1 regulates cellular and organismal senescence by inhibiting Forkhead box O transcription factors Aminoglycoside stress together with the 12S rRNA 1494C>T mutation leads to mitophagy.Mitochondrial DNA: impacting central and peripheral nervous systems.Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery Nuclear modifier MTO2 modulates the aminoglycoside-sensitivity of mitochondrial 15S rRNA C1477G mutation in Saccharomyces cerevisiae.Mitochondrial transcript maturation and its disorders An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis Mitochondrial retrograde signaling regulates neuronal function Mutations in LARS2, encoding mitochondrial leucyl-tRNA synthetase, lead to premature ovarian failure and hearing loss in Perrault syndrome.An authentic imaging probe to track cell fate from beginning to end.Mitochondria as a target of environmental toxicants.Epigenetic silencing mediates mitochondria stress-induced longevity.Mitochondrial retrograde signaling in the Drosophila nervous system and beyond.A Hypertension-Associated tRNAAla Mutation Alters tRNA Metabolism and Mitochondrial Function.Mitochondrial m.1584A 12S m62A rRNA methylation in families with m.1555A>G associated hearing loss.Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics.Metabolic regulation of the cell cycle.Overexpression of Twinkle-helicase protects cardiomyocytes from genotoxic stress caused by reactive oxygen species Muscle mitohormesis promotes longevity via systemic repression of insulin signaling.Oxalomalate reduces expression and secretion of vascular endothelial growth factor in the retinal pigment epithelium and inhibits angiogenesis: Implications for age-related macular degeneration.A deafness-associated tRNAAsp mutation alters the m1G37 modification, aminoacylation and stability of tRNAAsp and mitochondrial function.

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P2860

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

http://www.wikidata.org/entity/Q30458185

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2012 nî lūn-bûn

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2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի փետրվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

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name

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

@ast

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

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type

label

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

@ast

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

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prefLabel

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

@ast

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

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J.CELL.2011.12.027

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Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

@en

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David Hohuan

http://www.w3.org/2001/XMLSchema#string

Gerald S Shadel

http://www.w3.org/2001/XMLSchema#string

Joseph Santos-Sacchi

http://www.w3.org/2001/XMLSchema#string

Lei Song

http://www.w3.org/2001/XMLSchema#string

Min-Xin Guan

http://www.w3.org/2001/XMLSchema#string

Nuno Raimundo

http://www.w3.org/2001/XMLSchema#string

Sharen E McKay

http://www.w3.org/2001/XMLSchema#string

Thomas C Gilliland

http://www.w3.org/2001/XMLSchema#string

Timothy E Shutt

http://www.w3.org/2001/XMLSchema#string

P2860

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Human mitochondrial transcription factor B1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity

A human mitochondrial transcription factor is related to RNA adenine methyltransferases and binds S-adenosylmethionine

Relative abundance of the human mitochondrial transcription system and distinct roles for h-mtTFB1 and h-mtTFB2 in mitochondrial biogenesis and gene expression

Structural and Functional Divergence within the Dim1/KsgA Family of rRNA Methyltransferases

Efficient selection for high-expression transfectants with a novel eukaryotic vector

Summaries of Affymetrix GeneChip probe level data

Human mitochondrial transcription factor B1 methylates ribosomal RNA at a conserved stem-loop

Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

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716-726

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10.1016/J.CELL.2011.12.027

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4

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148

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apoptotic process

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3285425

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