Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation
about
Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant micePDE4 inhibitors: current statusStructures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitorsPrenatal environmental exposures, epigenetics, and diseaseMice deficient in phosphodiesterase-4A display anxiogenic-like behaviorPhosphodiesterase 4D and 5-lipoxygenase activating protein in ischemic stroke.Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay.Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arraysElevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophagesPhosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair.Aging-related hyperinflammation in endotoxemia is mediated by the alpha2A-adrenoceptor and CD14/TLR4 pathways.Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice.Advances in targeting cyclic nucleotide phosphodiesterasesGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.Phosphodiesterase 4B is essential for T(H)2-cell function and development of airway hyperresponsiveness in allergic asthmaDistinct roles of adenylyl cyclase VII in regulating the immune responses in miceCyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets.A selective phosphodiesterase-4 inhibitor reduces leukocyte infiltration, oxidative processes, and tissue damage after spinal cord injury.Contribution of mammary epithelial cells to the immune response during early stages of a bacterial infection to Staphylococcus aureus.Cross-talk between PKA-Cβ and p65 mediates synergistic induction of PDE4B by roflumilast and NTHi.Association between phosphodiesterase 4D (PDE4D) SNP 87 and ischemic stroke: a meta-analysis.The unrecognized effects of phosphodiesterase 4 on epithelial cells in pulmonary inflammation.A chemoattractant-mediated Gi-coupled pathway activates adenylyl cyclase in human neutrophils.Assessment of cellular mechanisms contributing to cAMP compartmentalization in pulmonary microvascular endothelial cells.Postinjury treatment with rolipram increases hemorrhage after traumatic brain injuryCyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies.Therapeutic benefits of phosphodiesterase 4B inhibition after traumatic brain injury.Phosphodiesterase isoform-specific expression induced by traumatic brain injury.Traumatic Brain Injury Upregulates Phosphodiesterase Expression in the Hippocampus.Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1.Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B).Dual PDE3/4 inhibitors as therapeutic agents for chronic obstructive pulmonary disease.No Association Between Single-Nucleotide Polymorphism 56 (SNP56) in Phosphodiesterase 4D (PDE4D) Gene and Susceptibility to Ischemic Stroke: A Meta-Analysis of 15 Studies.The novel distribution of phosphodiesterase-4 subtypes within the rat retina.Phosphodiesterase 4D single-nucleotide polymorphism 83 and cognitive dysfunction in carotid endarterectomy patients.Targeting cancer with phosphodiesterase inhibitors.Clinical and molecular genetics of the phosphodiesterases (PDEs).Dual PDE3/4 and PDE4 inhibitors: novel treatments for COPD and other inflammatory airway diseases.Phosphodiesterase inhibitors as therapeutics for traumatic brain injury.
P2860
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P2860
Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation
description
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Dezember 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/12/15)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/12/15)
@nl
наукова стаття, опублікована в грудні 2004
@uk
مقالة علمية (نشرت في 15-12-2004)
@ar
name
Nonredundant function of phosp ...... nt to the site of inflammation
@ast
Nonredundant function of phosp ...... nt to the site of inflammation
@en
Nonredundant function of phosp ...... nt to the site of inflammation
@nl
type
label
Nonredundant function of phosp ...... nt to the site of inflammation
@ast
Nonredundant function of phosp ...... nt to the site of inflammation
@en
Nonredundant function of phosp ...... nt to the site of inflammation
@nl
prefLabel
Nonredundant function of phosp ...... nt to the site of inflammation
@ast
Nonredundant function of phosp ...... nt to the site of inflammation
@en
Nonredundant function of phosp ...... nt to the site of inflammation
@nl
P2093
P3181
P1476
Nonredundant function of phosp ...... nt to the site of inflammation
@en
P2093
Barbara Neitzert
Claude Bertrand
Genevieve Mottin
Marco Conti
Marie Pierre Pruniaux
Miyako Ariga
S.-L. Catherine Jin
Susumu Nakae
P304
P3181
P356
10.4049/JIMMUNOL.173.12.7531
P407
P577
2004-12-15T00:00:00Z