P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating - Wikidata - awgldk - TriplyDB

P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating

P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating

http://www.wikidata.org/entity/Q30475074

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Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits Tau physiology and pathomechanisms in frontotemporal lobar degeneration Brain deposition and neurotoxicity of manganese in adult mice exposed via the drinking water.Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function.Genetic models of sensorimotor gating: relevance to neuropsychiatric disorders.Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau.High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model Granulocyte-macrophage colony-stimulating factor is neuroprotective in experimental traumatic brain injury Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity Role of Endoplasmic Reticulum Stress in Learning and Memory Impairment and Alzheimer's Disease-Like Neuropathology in the PS19 and APPSwe Mouse Models of Tauopathy and Amyloidosis.Contextual and cued fear conditioning test using a video analyzing system in mice.Barnes maze testing strategies with small and large rodent models.Proteopathic tau seeding predicts tauopathy in vivo.Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits Doubly Phosphorylated Peptide Vaccines to Protect Transgenic P301S Mice against Alzheimer's Disease Like Tau Aggregation.TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits.Early Cognitive/Social Deficits and Late Motor Phenotype in Conditional Wild-Type TDP-43 Transgenic Mice.Olfaction and olfactory-mediated behaviour in psychiatric disease models.Invited review: Animal models of tauopathies and their implications for research/translation into the clinic.Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model.Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.ALS/FTLD: experimental models and reality.Adult mice expressing a Braf Q241R mutation on an ICR/CD-1 background exhibit a cardio-facio-cutaneous syndrome phenotype.Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention.Motifs in the tau protein that control binding to microtubules and aggregation determine pathological effects Neuroinflammatory Gene Regulation, Mitochondrial Function, Oxidative Stress, and Brain Lipid Modifications With Disease Progression in Tau P301S Transgenic Mice as a Model of Frontotemporal Lobar Degeneration-Tau.Practical considerations for choosing a mouse model of Alzheimer's disease.Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo.Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice.Lack of exacerbation of neurodegeneration in a double transgenic mouse model of mutant LRRK2 and tau.Human Truncated Tau Induces Mature Neurofibrillary Pathology in a Mouse Model of Human Tauopathy.Progressive Motor Deficit is Mediated by the Denervation of Neuromuscular Junctions and Axonal Degeneration in Transgenic Mice Expressing Mutant (P301S) Tau Protein.Early intervention of tau pathology prevents behavioral changes in the rTg4510 mouse model of tauopathy.Cognitive Disorders: Impairment, Aging, and Dementia

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P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating

http://www.wikidata.org/entity/Q30475074

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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name

P301S mutant human tau transge ...... nd altered sensorimotor gating

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P301S mutant human tau transge ...... nd altered sensorimotor gating

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P301S mutant human tau transge ...... nd altered sensorimotor gating

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P301S mutant human tau transge ...... nd altered sensorimotor gating

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P301S mutant human tau transge ...... nd altered sensorimotor gating

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P301S mutant human tau transge ...... nd altered sensorimotor gating

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P301S mutant human tau transge ...... nd altered sensorimotor gating

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Haruhisa Inoue

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Hiroki Takeuchi

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Kayoko Tsukita

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Makoto Higuchi

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Michiyo Iba

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Yumiko Iwamoto

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P2860

Transmission and spreading of tauopathy in transgenic mouse brain

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

Impaired long-term memory retention and working memory in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia

Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

Are the dorsal and ventral hippocampus functionally distinct structures?

Projections from ventral hippocampus to medial prefrontal cortex but not nucleus accumbens remain functional after fornix lesions in rats

Pathways from the ventral hippocampus and caudal amygdala to forebrain regions that regulate sensorimotor gating in the rat.

Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders.

Abnormalities in brain structure and behavior in GSK-3alpha mutant mice

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