Proteopathic tau seeding predicts tauopathy in vivo. - Wikidata - awgldk - TriplyDB

Proteopathic tau seeding predicts tauopathy in vivo.

Proteopathic tau seeding predicts tauopathy in vivo.

http://www.wikidata.org/entity/Q34383788

about

Tau RD P301S FRET Biosensor

P1343

Propagation of prions causing synucleinopathies in cultured cells Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies Imaging Multimodalities for Dissecting Alzheimer's Disease: Advanced Technologies of Positron Emission Tomography and Fluorescence Imaging Blood biomarkers for brain injury: What are we measuring?The preclinical phase of the pathological process underlying sporadic Alzheimer's disease Propagation of tau pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.Glial contributions to neurodegeneration in tauopathies.Immunological memory to hyperphosphorylated tau in asymptomatic individuals.Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency Characterization of tau prion seeding activity and strains from formaldehyde-fixed tissue.Tau aggregation and its interplay with amyloid-β.Passive Immunization in JNPL3 Transgenic Mice Using an Array of Phospho-Tau Specific Antibodies.Activation of necroptosis in multiple sclerosis Progression of Seed-Induced Aβ Deposition within the Limbic Connectome Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in Mice Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain.Transport of cargo from periphery to brain by circulating monocytes.Characterization of TauC3 antibody and demonstration of its potential to block tau propagation Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity Detecting tau in serum of transgenic animal models after tau immunotherapy treatment.Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry α-Synuclein and huntingtin exon 1 amyloid fibrils bind laterally to the cellular membrane.Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner.Potential fluid biomarkers for pathological brain changes in Alzheimer's disease: Implication for the screening of cognitive frailty.Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43.Evidence of Tau Hyperphosphorylation and Dystrophic Microglia in the Common Marmoset.Prions and Protein Assemblies that Convey Biological Information in Health and Disease.Hierarchical Distribution of the Tau Cytoskeletal Pathology in the Thalamus of Alzheimer's Disease Patients.A mouse Model of Focal Vascular Injury Induces Astrocyte Reactivity, Tau Oligomers, and Aberrant Behavior.Intracellular and extracellular microtubule associated protein tau as a therapeutic target in Alzheimer disease and other tauopathies.Amyloid-β(1-42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity.Enhanced Tau Aggregation in the Presence of Amyloid β.Monoaminergic neuropathology in Alzheimer's disease.Potential Pathways of Abnormal Tau and α-Synuclein Dissemination in Sporadic Alzheimer's and Parkinson's Diseases.Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.Cellular Models for the Study of Prions.Molecular Genetics of Neurodegenerative Dementias.Therapeutic Strategies for Restoring Tau Homeostasis.Interactions of pathological proteins in neurodegenerative diseases.Molecular Chaperone Accumulation in Cancer and Decrease in Alzheimer's Disease: The Potential Roles of HSF1.

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P1343

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P2860

Proteopathic tau seeding predicts tauopathy in vivo.

http://www.wikidata.org/entity/Q34383788

description

2014 nî lūn-bûn

@nan

2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Proteopathic tau seeding predicts tauopathy in vivo.

@ast

Proteopathic tau seeding predicts tauopathy in vivo.

@en

Proteopathic tau seeding predicts tauopathy in vivo.

@nl

type

label

Proteopathic tau seeding predicts tauopathy in vivo.

@ast

Proteopathic tau seeding predicts tauopathy in vivo.

@en

Proteopathic tau seeding predicts tauopathy in vivo.

@nl

prefLabel

Proteopathic tau seeding predicts tauopathy in vivo.

@ast

Proteopathic tau seeding predicts tauopathy in vivo.

@en

Proteopathic tau seeding predicts tauopathy in vivo.

@nl

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PNAS.1411649111

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Proteopathic tau seeding predicts tauopathy in vivo

@en

P2093

David M Holtzman

http://www.w3.org/2001/XMLSchema#string

Hilda Mirbaha

http://www.w3.org/2001/XMLSchema#string

Jennifer L Furman

http://www.w3.org/2001/XMLSchema#string

Larisa Belaygorod

http://www.w3.org/2001/XMLSchema#string

Marc I Diamond

http://www.w3.org/2001/XMLSchema#string

Nigel J Cairns

http://www.w3.org/2001/XMLSchema#string

Tritia R Yamasaki

http://www.w3.org/2001/XMLSchema#string

William C Eades

http://www.w3.org/2001/XMLSchema#string

P2860

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

Transmission and spreading of tauopathy in transgenic mouse brain

Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic target

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

Neuropathological stageing of Alzheimer-related changes

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

Shattuck lecture--neurodegenerative diseases and prions

A general model of prion strains and their pathogenicity

Distinct α-synuclein strains differentially promote tau inclusions in neurons

Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuIC

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E4376-85

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scholarly article

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10.1073/PNAS.1411649111

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P407

P433

41

http://www.w3.org/2001/XMLSchema#string

P4510

Tau RD P301S FRET Biosensor

P478

111

http://www.w3.org/2001/XMLSchema#string

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Thomas E. Mahan

Brandon B Holmes

P577

2014-09-26T00:00:00Z

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266253136

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25261551

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4205609

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