Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4.
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Intracerebroventricular amyloid-beta antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 miceImpaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease.Network analysis of exploratory behaviors of mice in a spatial learning and memory task.Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD miceDNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model.CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic miceVersatile somatic gene transfer for modeling neurodegenerative diseases.A shortened Barnes maze protocol reveals memory deficits at 4-months of age in the triple-transgenic mouse model of Alzheimer's disease.HSV-1 amplicon vectors launch the production of heterologous rotavirus-like particles and induce rotavirus-specific immune responses in miceYeast expressed foldable quadrivalent Aβ15 elicited strong immune response against Aβ without Aβ-specific T cell response in wild C57BL/6 mice.Nasal immunization using a mimovirus vaccine based on the Eppin B-cell epitope induced suppressed fertility in mice.Anti-amyloid-beta immunotherapy in Alzheimer's disease: relevance of transgenic mouse studies to clinical trials.Immune-directed gene therapeutic development for Alzheimer's, prion, and Parkinson's diseases.Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease.Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease.Therapeutic potential of vaccines for Alzheimer's disease.Herpes Virus Amplicon Vectors.Effect of herpes simplex virus vector-mediated interleukin-4 gene therapy on bladder overactivity and nociception.Silibinin ameliorates Aβ25-35-induced memory deficits in rats by modulating autophagy and attenuating neuroinflammation as well as oxidative stress.
P2860
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P2860
Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Reduced pathology and improved ...... myloid-beta and interleukin-4.
@ast
Reduced pathology and improved ...... myloid-beta and interleukin-4.
@en
type
label
Reduced pathology and improved ...... myloid-beta and interleukin-4.
@ast
Reduced pathology and improved ...... myloid-beta and interleukin-4.
@en
prefLabel
Reduced pathology and improved ...... myloid-beta and interleukin-4.
@ast
Reduced pathology and improved ...... myloid-beta and interleukin-4.
@en
P2093
P2860
P356
P1433
P1476
Reduced pathology and improved ...... myloid-beta and interleukin-4.
@en
P2093
Howard J Federoff
Jennifer E Hughes
Jennifer L Tibbens
Maria E Frazer
Michael A Mastrangelo
William J Bowers
P2860
P304
P356
10.1038/MT.2008.39
P577
2008-03-11T00:00:00Z