Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice - Wikidata - awgldk - TriplyDB

Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice

Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice

http://www.wikidata.org/entity/Q33926242

about

The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic target Dietary DHA supplementation in an APP/PS1 transgenic rat model of AD reduces behavioral and Aβ pathology and modulates Aβ oligomerization Immunotherapeutic approaches for Alzheimer's disease A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses.Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer's disease mouse model.Tau aggregation and its interplay with amyloid-β.Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis.Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's disease Anti-Aβ antibodies incapable of reducing cerebral Aβ oligomers fail to attenuate spatial reference memory deficits in J20 mice.The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice Pseudomonas aeruginosa exoenzymes U and Y induce a transmissible endothelial proteinopathy A novel recombinant 6Aβ15-THc-C chimeric vaccine (rCV02) mitigates Alzheimer's disease-like pathology, cognitive decline and synaptic loss in aged 3 × Tg-AD mice.Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station.Should development of Alzheimer's disease-specific intravenous immunoglobulin be considered?Oligomeropathies and pathogenesis of Alzheimer and Parkinson's diseases.Innate immunity in Alzheimer's disease: the relevance of animal models?Production of Monoclonal Antibodies to Pathologic β-sheet Oligomeric Conformers in Neurodegenerative Diseases.Discrete pools of oligomeric amyloid-β track with spatial learning deficits in a mouse model of Alzheimer amyloidosis.Cognitive Decline in Preclinical Alzheimer's Disease: Amyloid-Beta versus Tauopathy.Tau Proteins and Tauopathies in Alzheimer's Disease.Amyloid β oligomers (AβOs) in Alzheimer's disease.An Intracellular Amyloid-β/AβPP Epitope Correlates with Neurodegeneration in those Neuronal Populations Early Involved in Alzheimer's Disease.Neural stem cell transplants improve cognitive function without altering amyloid pathology in an APP/PS1 double transgenic model of Alzheimer's disease.Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice.

P2860

Q26747107-2CC46DC5-AB8A-4694-A2CD-93EAE87C1062 Q27021159-52177BC0-BF54-4A36-ACFC-970A0B3F7C8F Q27307991-02A4BAC9-AFAB-4866-81DD-87EEC274B89E Q28081278-279732E3-D4C0-460D-9841-54AF6A561745 Q30827953-8D4593F8-96C3-4844-8269-C1B80FF9584B Q33640390-1530D33E-1413-43FC-8828-0DEEFA988EF3 Q34043432-85B0CC7C-CB12-40FE-86CC-66830687D6A1 Q35008256-A02E5738-1E2A-48AD-86D7-5885B8F91C0E Q35212180-311E2EF6-7947-451C-9E79-9776783E727B Q35327172-CE6BBB08-B3E1-4188-86DD-9B54117BBAA8 Q35643397-496CF065-629F-4ECA-920A-49CE34FB1F8A Q36269285-ED09F5ED-9DCB-4D0E-BC33-506395A8FFEE Q36393038-181DC9BE-640D-492E-BB19-32C443E64776 Q36583852-FF1ED0E5-3204-4880-8BAA-136D1605A98E Q36964826-BC4D8F74-B906-489D-A2A6-FE03EA6B05DF Q37724402-59E2A4F0-B4A3-4F76-9C12-AF41E254BF6C Q38283308-A9F7FC1A-7A26-4053-9BEB-D97725C3A824 Q38794219-DCC50000-9965-4B47-B0BA-503014C27235 Q39314130-99670E68-05EF-43C5-8C4F-D35F37F4D37B Q41548991-B94DD9E4-29AD-4228-AB64-732ACC3ECFA5 Q46238269-78E7FF95-3762-44C2-8A52-F68180E90423 Q47110701-C805104F-CC45-47AF-87FF-A53DD14E2903 Q47233523-C644D305-EBDB-46AD-B089-572C06530CE7 Q47339779-918C0433-C3C8-4BED-83A0-E69FA579D2E0 Q47975769-B9D6B0FD-559B-4DE0-A94D-AA8DD6CC535D Q50692044-A9D8C0BC-6D09-445C-B464-B039EAF37EA9 Q53416393-5C2891EC-DFAD-4BC0-8955-F24093816C38

P2860

Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice

http://www.wikidata.org/entity/Q33926242

description

2013 nî lūn-bûn

@nan

2013 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Systemic vaccination with anti ...... tau pathology in 3xTg-AD mice

@ast

Systemic vaccination with anti ...... tau pathology in 3xTg-AD mice

@en

type

label

Systemic vaccination with anti ...... tau pathology in 3xTg-AD mice

@ast

Systemic vaccination with anti ...... tau pathology in 3xTg-AD mice

@en

prefLabel

Systemic vaccination with anti ...... tau pathology in 3xTg-AD mice

@ast

Systemic vaccination with anti ...... tau pathology in 3xTg-AD mice

@en

P1433

Q33926242-35E37FAB-3B22-4203-90B9-508AE0016F03

P1476

Q33926242-154755C0-2919-42DB-BB0D-B3B971DD8401

P2093

Q33926242-23B19A06-1663-4F1E-8EBD-B7DF3ECAC9D0

Q33926242-30007D95-59B2-4972-B3FA-B92AAB0EA13D

Q33926242-381C9F92-5F9D-4027-8654-B602A817A177

Q33926242-CC2F740D-1764-4E33-8CCB-7377946F0AC7

P2860

Q33926242-0160CEA9-95DD-493F-8B5E-B8C02B9FF696

Q33926242-0ABF0B0E-E9F3-46E5-ADC6-75124E0E269B

Q33926242-12740338-1853-4D51-86B0-D87F4CA1B7E6

Q33926242-13419080-6876-4FD3-BEEC-2D88B1E6C42D

Q33926242-163A1410-1819-4936-B6F4-E510AC02EEF2

Q33926242-16A2AB42-824F-4EDA-92D6-A68AFC24E4A7

Q33926242-1D6D1430-2E9D-4A6E-9051-D5595D225B4C

Q33926242-27DC1BCB-1CC7-4AE1-A69F-258EDCA60206

Q33926242-2F59D92C-25A6-4172-9C9B-5F0C8A42A297

Q33926242-30FCD46B-B39D-44AA-9247-7AD891E0C4C8

P304

Q33926242-75993F56-5085-41FB-BEEB-FE8128C4AF22

P31

Q33926242-29B6255A-81D4-46F9-A2EF-E6EDBCE6D8E2

P356

Q33926242-6E964430-F467-4AF7-A3CB-F3F7BAC5F2E3

P407

Q33926242-D3FE47E6-CEC0-4546-98C3-F4215ACAF001

P433

Q33926242-F754517B-56F5-49E6-AEF0-AE2125E6C652

P478

Q33926242-23AAD74C-DE84-4053-A074-0367608C0779

P50

Q33926242-361BECDA-A8F5-412B-9DA2-97BBA710B47E

P577

Q33926242-5683F45E-6942-4D70-830A-F749D5688AB6

P698

Q33926242-3BC548F0-672E-40FF-8A22-08D517F32B13

P932

Q33926242-A9D4349A-5D07-404F-8B73-F6A43660CD11

P356

P1433

Journal of Neurochemistry

P1476

Systemic vaccination with anti ...... tau pathology in 3xTg-AD mice

@en

P2093

Charles G Glabe

http://www.w3.org/2001/XMLSchema#string

Frank LaFerla

http://www.w3.org/2001/XMLSchema#string

Jessica W Wu

http://www.w3.org/2001/XMLSchema#string

Suhail Rasool

http://www.w3.org/2001/XMLSchema#string

P2860

Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

Active and passive immunotherapy for neurodegenerative disorders

Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Tau reduction prevents Abeta-induced defects in axonal transport.

Altered microtubule organization in small-calibre axons of mice lacking tau protein

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

Alzheimer's disease

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

P304

473-482

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1111/JNC.12305

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

126

http://www.w3.org/2001/XMLSchema#string

P50

Hilda Martínez-Coria

P577

2013-06-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23672786

http://www.w3.org/2001/XMLSchema#string

P932

4105004

http://www.w3.org/2001/XMLSchema#string