Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease.
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Innate immunity in Alzheimer's disease: a complex affairAmyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive declinePromoting nerve regeneration in a neurotmesis rat model using poly(DL-lactide-ε-caprolactone) membranes and mesenchymal stem cells from the Wharton's jelly: in vitro and in vivo analysis.Granulocyte-macrophage colony-stimulating factor antibody suppresses microglial activity: implications for anti-inflammatory effects in Alzheimer's disease and multiple sclerosisDifferences in abundances of cell-signalling proteins in blood reveal novel biomarkers for early detection of clinical Alzheimer's diseaseCX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons.Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.Mitochondrial DNA deletions and differential mitochondrial DNA content in Rhesus monkeys: implications for agingMitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension.Young microglia restore amyloid plaque clearance of aged microglia.GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia.MitoQ, a mitochondria-targeted antioxidant, delays disease progression and alleviates pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis.RNA silencing of genes involved in Alzheimer's disease enhances mitochondrial function and synaptic activity.Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells.Review: experimental manipulations of microglia in mouse models of Alzheimer's pathology: activation reduces amyloid but hastens tau pathology.Should development of Alzheimer's disease-specific intravenous immunoglobulin be considered?Emerging treatments for Alzheimer's disease for non-amyloid and non-tau targets.Targeting granulocyte-macrophage colony-stimulating factor in epithelial and vascular remodeling in experimental eosinophilic esophagitis.Intracerebral GM-CSF contributes to transendothelial monocyte migration in APP/PS1 Alzheimer's disease miceGranulocyte macrophage colony-stimulating factor promotes regeneration of retinal ganglion cells in vitro through a mammalian target of rapamycin-dependent mechanism.
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P2860
Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 19 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Neutralization of granulocyte ...... model of Alzheimer's disease.
@en
Neutralization of granulocyte ...... model of Alzheimer's disease.
@nl
type
label
Neutralization of granulocyte ...... model of Alzheimer's disease.
@en
Neutralization of granulocyte ...... model of Alzheimer's disease.
@nl
prefLabel
Neutralization of granulocyte ...... model of Alzheimer's disease.
@en
Neutralization of granulocyte ...... model of Alzheimer's disease.
@nl
P2093
P2860
P921
P356
P1476
Neutralization of granulocyte ...... model of Alzheimer's disease.
@en
P2093
Byung Park
Christopher Bebbington
Kazuhiro Nakamura
Maria Manczak
P Hemachandra Reddy
Peizhong Mao
P2860
P304
P356
10.1093/HMG/DDP331
P577
2009-07-19T00:00:00Z