Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion - Wikidata - awgldk - TriplyDB

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

http://www.wikidata.org/entity/Q30497339

about

Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts Tricyclic Benzo[cd]azulenes selectively inhibit activities of Pim kinases and restrict growth of Epstein-Barr virus-transformed cells A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas PIM1 kinase as a target for cancer therapy PIM1 polymorphism and PIM1 expression as predisposing factors of esophageal squamous cell carcinoma in the Asian population.Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells.The PIM family of serine/threonine kinases in cancer.ZFP36 expression impairs glioblastoma cell lines viability and invasiveness by targeting multiple signal transduction pathways.Clinical and therapeutic relevance of PIM1 kinase in gastric cancer.PIM-1 mRNA expression is a potential prognostic biomarker in acute myeloid leukemia.Kaposi's sarcoma herpesvirus lytic replication compromises apoptotic response to p53 reactivation in virus-induced lymphomas.QSAR study and rustic ligand-based virtual screening in a search for aminooxadiazole derivatives as PIM1 inhibitors.

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P2860

Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

http://www.wikidata.org/entity/Q30497339

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

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Pim-selective inhibitor DHPCC- ...... er cell migration and invasion

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Pim-selective inhibitor DHPCC- ...... er cell migration and invasion

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Pim-selective inhibitor DHPCC- ...... er cell migration and invasion

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Molecular Cancer

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Pim-selective inhibitor DHPCC- ...... er cell migration and invasion

@en

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Eeva-Marja Rainio

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Fabrice Anizon

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Jouko A Sandholm

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Michelle Prudhomme

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Niina M Santio

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Pascale Moreau

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Päivi J Koskinen

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Riitta L Vahakoski

http://www.w3.org/2001/XMLSchema#string

Sanna S Virtanen

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P2860

Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

The human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemias

Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors

PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers

Pim1 kinase synergizes with c-MYC to induce advanced prostate carcinoma

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase

Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity

Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode

Synthesis, kinase inhibitory potencies, and in vitro antiproliferative evaluation of new Pim kinase inhibitors

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9

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2010-10-19T00:00:00Z

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