Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells
about
Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycleSuppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCKQuantitation and Identification of Thousands of Human Proteoforms below 30 kDaMechanisms of genome instability induced by RNA-processing defects.Development of siRNA payloads to target KRAS-mutant cancer.Selective targeting of KRAS-mutant cells by miR-126 through repression of multiple genes essential for the survival of KRAS-mutant cellsIdentification of amino acid residues of ERH required for its recruitment to nuclear speckles and replication foci in HeLa cellsIdentification of the GTPase-activating protein DEP domain containing 1B (DEPDC1B) as a transcriptional target of Pitx2Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9.Enhancer of rudimentary homolog regulates DNA damage response in hepatocellular carcinomaEnhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA ProcessingThe enigmatic ERH protein: its role in cell cycle, RNA splicing and cancer.Drosophila Enhancer of Rudimentary Homolog, ERH, Is a Binding Partner of RPS3, RPL19, and DDIT4, Suggesting a Mechanism for the Nuclear Localization of ERH.A genotoxic stress-responsive miRNA, miR-574-3p, delays cell growth by suppressing the enhancer of rudimentary homolog gene in vitro.Defeat mutant KRAS with synthetic lethality.Proteomic analysis of polyribosomes identifies splicing factors as potential regulators of translation during mitosis.Enhancer of rudimentary homologue interacts with scaffold attachment factor B at the nuclear matrix to regulate SR protein phosphorylation.KRAS Cold Turkey: Using microRNAs to target KRAS-addicted cancer.A recently evolved class of alternative 3'-terminal exons involved in cell cycle regulation by topoisomerase inhibitors.
P2860
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P2860
Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Evolutionarily conserved prote ...... al of KRAS mutant cancer cells
@ast
Evolutionarily conserved prote ...... al of KRAS mutant cancer cells
@en
type
label
Evolutionarily conserved prote ...... al of KRAS mutant cancer cells
@ast
Evolutionarily conserved prote ...... al of KRAS mutant cancer cells
@en
prefLabel
Evolutionarily conserved prote ...... al of KRAS mutant cancer cells
@ast
Evolutionarily conserved prote ...... al of KRAS mutant cancer cells
@en
P2093
P2860
P356
P1476
Evolutionarily conserved prote ...... al of KRAS mutant cancer cells
@en
P2093
Aaron J Schetter
Chad J Creighton
Christina M Annunziata
Curtis C Harris
Dennis Hsu
Jih-Hsiang Lee
Marianne K H Kim
Marjan Gucek
Meng-Tzu Weng
P2860
P304
P356
10.1073/PNAS.1207673110
P407
P577
2012-12-10T00:00:00Z