Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway - Wikidata - awgldk - TriplyDB

Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway

Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway

http://www.wikidata.org/entity/Q30540604

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Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF.Endothelial Cells Use a Formin-Dependent Phagocytosis-Like Process to Internalize the Bacterium Listeria monocytogenes F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions.Biomechanics of vascular mechanosensation and remodeling E-cadherin-mediated force transduction signals regulate global cell mechanics Local VE-cadherin mechanotransduction triggers long-ranged remodeling of endothelial monolayers.Flow-dependent cellular mechanotransduction in atherosclerosis.Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells.TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion.Regulation of endothelial cell barrier function by antibody-driven affinity modulation of platelet endothelial cell adhesion molecule-1 (PECAM-1)Platelet endothelial cell adhesion molecule-1 mediates endothelial-cardiomyocyte communication and regulates cardiac function.Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim Mechanosensing at the vascular interface.Structural Determinants of the Mechanical Stability of α-Catenin.PECAM-1 isoforms, eNOS and endoglin axis in regulation of angiogenesis Using magnets and magnetic beads to dissect signaling pathways activated by mechanical tension applied to cells Structural basis for PECAM-1 homophilic binding.Oxidized LDL signals through Rho-GTPase to induce endothelial cell stiffening and promote capillary formation.Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31).Haemodynamics Regulate Fibronectin Assembly via PECAM.Advances in magnetic tweezers for single molecule and cell biophysics.PECAM-1: regulator of endothelial junctional integrity.Regulation of RhoA activity by adhesion molecules and mechanotransduction.Endothelial mechanosensors: the gatekeepers of vascular homeostasis and adaptation under mechanical stress.The influence of a spatiotemporal 3D environment on endothelial cell differentiation of human induced pluripotent stem cells Fluid shear stress induces upregulation of COX-2 and PGI2 release in endothelial cells via a pathway involving PECAM-1, PI3K, FAK, and p38.Endothelial CD2AP Binds the Receptor ICAM-1 To Control Mechanosignaling, Leukocyte Adhesion, and the Route of Leukocyte Diapedesis In Vitro.The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads.Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1.Endothelial Mechanosignaling: Does One Sensor Fit All?Cell-cell junctional mechanotransduction in endothelial remodeling.A single gene connects stiffness in glaucoma and the vascular system.Leukocyte transendothelial migration: A local affair.Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability.Biomechanical factors in atherosclerosis: mechanisms and clinical implications.The role of apical cell-cell junctions and associated cytoskeleton in mechanotransduction.Biophysical Tools to Study Cellular Mechanotransduction.Mechanotransduction of shear stress occurs through changes in VE-cadherin and PECAM-1 tension: implications for cell migration.

P2860

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P2860

Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway

http://www.wikidata.org/entity/Q30540604

description

2012 nî lūn-bûn

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2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Localized tensional forces on ...... via the integrin-RhoA pathway

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Localized tensional forces on ...... via the integrin-RhoA pathway

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Localized tensional forces on ...... via the integrin-RhoA pathway

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J.CUB.2012.08.051

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Current Biology

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Localized tensional forces on ...... via the integrin-RhoA pathway

@en

P2093

Caitlin Collins

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Christopher Welch

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E Timothy O'Brien

http://www.w3.org/2001/XMLSchema#string

Ellie Tzima

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Keith Burridge

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Klaus Hahn

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P2860

Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule 1.

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion.

Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment

Rapid activation of Rac GTPase in living cells by force is independent of Src

Identification of alpha v beta 3 as a heterotypic ligand for CD31/PECAM-1

Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

Coordination of Rho GTPase activities during cell protrusion

Spatiotemporal dynamics of RhoA activity in migrating cells

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

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2087-2094

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scholarly article

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10.1016/J.CUB.2012.08.051

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22

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22

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Christophe Guilluy

Richard Superfine

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2012-10-18T00:00:00Z

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232530821

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23084990

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P921

Mechanotransduction

P932

3681294

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