Selective targeting of the α5-subunit of GABAA receptors relaxes airway smooth muscle and inhibits cellular calcium handling

Selective targeting of the α5-subunit of GABAA receptors relaxes airway smooth muscle and inhibits cellular calcium handling

Item
http://www.wikidata.org/entity/Q30647960
A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor ModelEster to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit.Analysis of β-Subunit-dependent GABAA Receptor Modulation and Behavioral Effects of Valerenic Acid Derivatives.Targeting the γ-Aminobutyric Acid A Receptor α4 Subunit in Airway Smooth Muscle to Alleviate Bronchoconstriction.Development of GABAA Receptor Subtype-Selective Imidazobenzodiazepines as Novel Asthma TreatmentsAirway Epithelial Cell Release of GABA is Regulated by Protein Kinase A.GABAA receptor α4-subunit knockout enhances lung inflammation and airway reactivity in a murine asthma model.Emerging concepts in smooth muscle contributions to airway structure and function: implications for health and disease.Bronchoprotection and bronchorelaxation in asthma: New targets, and new ways to target the old ones.Influenza virus infection alters ion channel function of Airway and alveolar cells: Mechanisms and physiological sequelae.Ion channels of the lung and their role in disease pathogenesis.Optimization of substituted imidazobenzodiazepines as novel asthma treatments.Alleviation of Multiple Asthmatic Pathologic Features with Orally Available and Subtype Selective GABAA Receptor Modulators.Molecular Characterization of GABA-A Receptor Subunit Diversity within Major Peripheral Organs and Their Plasticity in Response to Early Life Psychosocial Stress.A Novel Orally Available Asthma Drug Candidate That Reduces Smooth Muscle Constriction and Inflammation by Targeting GABAA Receptors in the Lung.
P2860

Selective targeting of the α5-subunit of GABAA receptors relaxes airway smooth muscle and inhibits cellular calcium handling

Item
http://www.wikidata.org/entity/Q30647960
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Selective targeting of the α5- ...... bits cellular calcium handling
@ast
Selective targeting of the α5- ...... bits cellular calcium handling
@en
type
label
Selective targeting of the α5- ...... bits cellular calcium handling
@ast
Selective targeting of the α5- ...... bits cellular calcium handling
@en
prefLabel
Selective targeting of the α5- ...... bits cellular calcium handling
@ast
Selective targeting of the α5- ...... bits cellular calcium handling
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Selective targeting of the α5- ...... bits cellular calcium handling
@en
P2093
P2860
P304
P31
P356
10.1152/AJPLUNG.00107.2014
P433
P478
P50
P577
P5875
P698
P932