A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors - Wikidata - awgldk - TriplyDB

A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors

A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors

http://www.wikidata.org/entity/Q30662775

about

Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests.Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration.Highlight report: Erroneous sample annotation in a high fraction of publicly available genome-wide expression datasets Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells.Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay Expression classifiers for developmental toxicants.Identification of carcinogens by a selected panel of DNA damage response associated genes.Embryonic stem cells and the next generation of developmental toxicity testing.In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities.Highlight report: Cardiotoxicity screening.Adverse outcome pathways: opportunities, limitations and open questions Highlight report: Launch of a large integrated European in vitro toxicology project: EU-ToxRisk.Whole genome microarray analysis of neural progenitor C17.2 cells during differentiation and validation of 30 neural mRNA biomarkers for estimation of developmental neurotoxicity.Editor's Highlight: Development of Novel Neural Embryonic Stem CellTests for High-Throughput Screening of Embryotoxic Chemicals.Stem cells in toxicological research.Efficacy of hydralazine and valproate in cutaneous T-cell lymphoma, a phase II study.Ensemble of rankers for efficient gene signature extraction in smoke exposure classification.Highlight report: acetaminophen hepatotoxicity.Highlight report: pluripotent stem cells in translational research.

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P2860

A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors

http://www.wikidata.org/entity/Q30662775

description

2015 nî lūn-bûn

@nan

2015 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年論文

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2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

A transcriptome-based classifi ...... histone deacetylase inhibitors

@ast

A transcriptome-based classifi ...... histone deacetylase inhibitors

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type

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A transcriptome-based classifi ...... histone deacetylase inhibitors

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A transcriptome-based classifi ...... histone deacetylase inhibitors

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prefLabel

A transcriptome-based classifi ...... histone deacetylase inhibitors

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A transcriptome-based classifi ...... histone deacetylase inhibitors

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Archives of Toxicology

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A transcriptome-based classifi ...... histone deacetylase inhibitors

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Eugen Rempel

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Johannes Meisig

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John Antony Das Gaspar

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Julia Liebing

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Lisa Hoelting

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Marianna Grinberg

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Nina V Balmer

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Regina Stöber

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Stefan Schildknecht

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Tanja Waldmann

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P2860

Consensus report on the future of animal-free systemic toxicity testing

Modeling chemotherapeutic neurotoxicity with human induced pluripotent stem cell-derived neuronal cells

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Embryonic stem cell lines derived from human blastocysts

Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities

Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts

MicroRNA profiling as tool for in vitro developmental neurotoxicity testing: the case of sodium valproate

Adjusting batch effects in microarray expression data using empirical Bayes methods

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

JASPAR 2010: the greatly expanded open-access database of transcription factor binding profiles

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s00204-015-1573-y

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1599-1618

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9

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89

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Jörg Rahnenführer

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Jan G Hengstler

Agapios Sachinidis

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2015-08-14T00:00:00Z

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