Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node.
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Pacemaker channel dysfunction in a patient with sinus node diseaseHypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels.Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testisMolecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4Different roles for the cyclic nucleotide binding domain and amino terminus in assembly and expression of hyperpolarization-activated, cyclic nucleotide-gated channelsDifferential and age-dependent expression of hyperpolarization-activated, cyclic nucleotide-gated cation channel isoforms 1-4 suggests evolving roles in the developing rat hippocampusProperties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotideCalcium-dependent binding of HCN1 channel protein to hair cell stereociliary tip link protein protocadherin 15 CD3HCN1 and HCN2 proteins are expressed in cochlear hair cells: HCN1 can form a ternary complex with protocadherin 15 CD3 and F-actin-binding filamin A or can interact with HCN2The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart.The cardiac pacemaker-specific channel Hcn4 is a direct transcriptional target of MEF2Functional contributions of HCN channels in the primary auditory neurons of the mouse inner ear.GLI3 repressor controls functional development of the mouse ureterA molecular signature of tissues with pacemaker activity in the heart and upper urinary tract involves coexpressed hyperpolarization-activated cation and T-type Ca2+ channels.The pelvis-kidney junction contains HCN3, a hyperpolarization-activated cation channel that triggers ureter peristalsis.Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes.Serotonin modulates spike probability in the axon initial segment through HCN channels.The Ih Channel Gene Promotes Synaptic Transmission and Coordinated Movement in Drosophila melanogaster.A single histidine residue determines the pH sensitivity of the pacemaker channel HCN2.Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia.K+ channel regulator KCR1 suppresses heart rhythm by modulating the pacemaker current If.P-loop residues critical for selectivity in K channels fail to confer selectivity to rabbit HCN4 channels.Cation and voltage dependence of lidocaine inhibition of the hyperpolarization-activated cyclic nucleotide-gated HCN1 channel.Pacemaker oscillations in heart and brain: a key role for hyperpolarization-activated cation channels.Regulated expression of HCN channels and cAMP levels shape the properties of the h current in developing rat hippocampusA novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews.Expression and distribution of voltage-gated ion channels in ferret sinoatrial nodeA homology model of the pore region of HCN channels.Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivationFunctional expression of the human HCN3 channel.Asymmetric divergence in structure and function of HCN channel duplicates in Ciona intestinalis.Properties of ivabradine-induced block of HCN1 and HCN4 pacemaker channels.The fast and slow ups and downs of HCN channel regulation.Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mousecAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore.The expression and role of hyperpolarization-activated and cyclic nucleotide-gated channels in endocrine anterior pituitary cells.Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker.Functional Characterization of Cnidarian HCN Channels Points to an Early Evolution of Ih.Electrophysiological analysis of mammalian cells expressing hERG using automated 384-well-patch-clamp.Developmental febrile seizures modulate hippocampal gene expression of hyperpolarization-activated channels in an isoform- and cell-specific manner.
P2860
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P2860
Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node.
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Molecular characterization of ...... rabbit heart sinoatrial node.
@ast
Molecular characterization of ...... rabbit heart sinoatrial node.
@en
type
label
Molecular characterization of ...... rabbit heart sinoatrial node.
@ast
Molecular characterization of ...... rabbit heart sinoatrial node.
@en
prefLabel
Molecular characterization of ...... rabbit heart sinoatrial node.
@ast
Molecular characterization of ...... rabbit heart sinoatrial node.
@en
P2093
P356
P1476
Molecular characterization of ...... rabbit heart sinoatrial node.
@en
P2093
P304
12835-12839
P356
10.1074/JBC.274.18.12835
P407
P577
1999-04-01T00:00:00Z