Randomization of the receptor alpha chain recruitment epitope reveals a functional interleukin-5 with charge depletion in the CD loop.
about
Structural basis of interleukin-5 dimer recognition by its α receptorCoiled coil miniprotein randomization on phage leads to charge pattern mimicry of the receptor recognition determinant of interleukin 5.The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling.SiteLight: binding-site prediction using phage display libraries.Neutralizing monoclonal antibodies can potentiate IL-5 signaling.Kinetic interaction analysis of human interleukin 5 receptor alpha mutants reveals a unique binding topology and charge distribution for cytokine recognition.Epitope randomization redefines the functional role of glutamic acid 110 in interleukin-5 receptor activation.
P2860
Q27678698-3CA84166-C8AD-4A56-A30B-E25BD0CB2FC7Q32064627-BD2F539F-24F5-4F65-AE65-9032CD05A7BEQ34304678-E8E6DD96-9A56-4E2D-A027-04A8F7946C2BQ36572145-A732D19A-5021-447C-94FC-7EBA8932A847Q40813340-7052C59C-2932-45AC-B867-95C4D8C05908Q51598582-0AB27476-37E2-4A12-AE9B-F4ABF85DD0CAQ54047807-CB5247A3-E712-4809-B2D0-F2220A47E4AA
P2860
Randomization of the receptor alpha chain recruitment epitope reveals a functional interleukin-5 with charge depletion in the CD loop.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Randomization of the receptor ...... arge depletion in the CD loop.
@ast
Randomization of the receptor ...... arge depletion in the CD loop.
@en
type
label
Randomization of the receptor ...... arge depletion in the CD loop.
@ast
Randomization of the receptor ...... arge depletion in the CD loop.
@en
prefLabel
Randomization of the receptor ...... arge depletion in the CD loop.
@ast
Randomization of the receptor ...... arge depletion in the CD loop.
@en
P2093
P2860
P356
P1476
Randomization of the receptor ...... arge depletion in the CD loop.
@en
P2093
Canziani G
P2860
P304
20479-20488
P356
10.1074/JBC.274.29.20479
P407
P577
1999-07-01T00:00:00Z