Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.
about
Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cellsDirect association of the unique C-terminal tail of transmembrane AMPA receptor regulatory protein γ-8 with calcineurinTranscription of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase type 3 gene, ATP2A3, is regulated by the calcineurin/NFAT pathway in endothelial cellsCalcineurin/Nfat signaling is required for perinatal lung maturation and functionSH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55Use of Cell-Penetrating Peptides in Dendritic Cell-Based VaccinationTherapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorderNuclear factor of activated T cells - a transcription factor family as critical regulator in lung and colon cancerCalcineurin/NFAT signaling and innate host defence: a role for NOD1-mediated phagocytic functionsStabilin-2 modulates the efficiency of myoblast fusion during myogenic differentiation and muscle regeneration.Structure of the Calcineurin-NFAT Complex: Defining a T Cell Activation Switch Using Solution NMR and Crystal CoordinatesThe Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of CalcineurinBalanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signalingHph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae.Requirement of two NFATc4 transactivation domains for CBP potentiationThe p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathwayInside-out Ca(2+) signalling prompted by STIM1 conformational switch.Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophyIREM-1 is a novel inhibitory receptor expressed by myeloid cellsMultiple cytokines sharing the common receptor gamma chain can induce CD154/CD40 ligand expression by human CD4+ T lymphocytes via a cyclosporin A-resistant pathwayCalcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycleOverlapping role of dynamin isoforms in synaptic vesicle endocytosisInhibition of G-protein βγ signaling enhances T cell receptor-stimulated interleukin 2 transcription in CD4+ T helper cellsCalcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl IsomerizationAKAP79/150 anchoring of calcineurin controls neuronal L-type Ca2+ channel activity and nuclear signalingNovel interactions between NFATc1 (Nuclear Factor of Activated T cells c1) and STAT-3 (Signal Transducer and Activator of Transcription-3) mediate G protein-coupled receptor agonist, thrombin-induced biphasic expression of cyclin D1, with first phasThe nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targetedNFATc1 targets cyclin A in the regulation of vascular smooth muscle cell multiplication during restenosisDoxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calciumCalcium-dependent activation of nuclear factor regulated by interleukin 3/adenovirus E4 promoter-binding protein gene expression by calcineurin/nuclear factor of activated T cells and calcium/calmodulin-dependent protein kinase signalingActivity-dependent repression of muscle genes by NFATRegulation of GATA-3 expression during CD4 lineage differentiation.Defective T cell development and function in calcineurin A beta -deficient miceCooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesisA second calcineurin binding site on the NFAT regulatory domainNFAT2 inhibitor ameliorates diabetic nephropathy and podocyte injury in db/db mice3BP2 adapter protein is required for receptor activator of NFκB ligand (RANKL)-induced osteoclast differentiation of RAW264.7 cells.Genome-wide microarray analyses identify the protein C receptor as a novel calcineurin/nuclear factor of activated T cells-dependent gene in vascular smooth muscle cell phenotypic modulation.The divergence, actions, roles, and relatives of sodium-coupled bicarbonate transportersDistinct temporal patterns of T cell receptor signaling during positive versus negative selection in situ
P2860
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P2860
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.
@ast
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.
@en
type
label
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.
@ast
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.
@en
prefLabel
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.
@ast
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.
@en
P2093
P1433
P1476
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.
@en
P2093
C López-Rodríguez
J Aramburu
P304
P356
10.1126/SCIENCE.285.5436.2129
P407
P577
1999-09-01T00:00:00Z