Emergence of diverse biochemical activities in evolutionarily conserved structural scaffolds of proteins.
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Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymesPhylogenetic profiling of the Arabidopsis thaliana proteome: what proteins distinguish plants from other organisms?Natural history of S-adenosylmethionine-binding proteinsAtomic model of human Rcd-1 reveals anarmadillo-like-repeat protein with in vitro nucleic acid binding propertiesA Novel Function for the N-Terminal Nucleophile Hydrolase Fold Demonstrated by the Structure of an Archaeal Inosine Monophosphate Cyclohydrolase † , ‡Function, Structure, and Evolution of the RubisCO-Like Proteins and Their RubisCO HomologsRole of Bacillus subtilis BacB in the Synthesis of BacilysinHow much of protein sequence space has been explored by life on Earth?The TIM Barrel Architecture Facilitated the Early Evolution of Protein-Mediated MetabolismDistribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discoveryAspartyl Oxidation Catalysts That Dial In Functional Group Selectivity, along with Regio- and StereoselectivityMany paths to methyltransfer: a chronicle of convergenceInsights into the fold organization of TIM barrel from interaction energy based structure networksProtein structure similarity as guiding principle for combinatorial library design.Protein dynamism and evolvability.ProSMoS server: a pattern-based search using interaction matrix representation of protein structuresDiscrete-continuous duality of protein structure space.Functional insight into Maelstrom in the germline piRNA pathway: a unique domain homologous to the DnaQ-H 3'-5' exonuclease, its lineage-specific expansion/loss and evolutionarily active site switch.Analysis and prediction of functionally important sites in proteins.Small but versatile: the extraordinary functional and structural diversity of the beta-grasp foldThe RAGNYA fold: a novel fold with multiple topological variants found in functionally diverse nucleic acid, nucleotide and peptide-binding proteinsEvolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems.One origin for metallo-β-lactamase activity, or two? An investigation assessing a diverse set of reconstructed ancestral sequences based on a sample of phylogenetic trees.Phylogenomic analysis of glycogen branching and debranching enzymatic duoProtein similarity networks reveal relationships among sequence, structure, and function within the Cupin superfamily.The Drosophila Bruno paralogue Bru-3 specifically binds the EDEN translational repression element.Resilience of biochemical activity in protein domains in the face of structural divergence.Biochemical functional predictions for protein structures of unknown or uncertain functionSystematic assessment of accuracy of comparative model of proteins belonging to different structural fold classes.Clusters of branched aliphatic side chains serve as cores of stability in the native state of the HisF TIM barrel protein.The dynamic determinants of reaction specificity in the IMPDH/GMPR family of (β/α)(8) barrel enzymes.Applications of Nonenzymatic Catalysts to the Alteration of Natural Products.Molecular phylogenetics and functional evolution of major RNA recognition domains of recently cloned and characterized autoimmune RNA-binding particle.Crystallographic analysis of a cupin superfamily enzyme from Microcystis aeruginosa involved in aeruginosin biosynthesis.When the Scaffold Cannot Be Ignored: The Role of the Hydrophobic Core in Ligand Binding and Specificity.Enantioselective sulfonylation reactions mediated by a tetrapeptide catalyst.Probing the origin of the compromised catalysis of E. coli alkaline phosphatase in its promiscuous sulfatase reaction.Crystallization and preliminary X-ray diffraction studies on the bicupin YwfC from Bacillus subtilis.Complete characterization of the seventeen step moenomycin biosynthetic pathway.Structural insights into substrate selectivity of ribosomal RNA methyltransferase RlmCD.
P2860
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P2860
Emergence of diverse biochemical activities in evolutionarily conserved structural scaffolds of proteins.
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Emergence of diverse biochemic ...... uctural scaffolds of proteins.
@ast
Emergence of diverse biochemic ...... uctural scaffolds of proteins.
@en
type
label
Emergence of diverse biochemic ...... uctural scaffolds of proteins.
@ast
Emergence of diverse biochemic ...... uctural scaffolds of proteins.
@en
prefLabel
Emergence of diverse biochemic ...... uctural scaffolds of proteins.
@ast
Emergence of diverse biochemic ...... uctural scaffolds of proteins.
@en
P50
P1476
Emergence of diverse biochemic ...... uctural scaffolds of proteins.
@en
P356
10.1016/S1367-5931(02)00018-2
P577
2003-02-01T00:00:00Z