Identification of novel essential Escherichia coli genes conserved among pathogenic bacteria.
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A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzaeFrom genetic footprinting to antimicrobial drug targets: examples in cofactor biosynthetic pathwaysCharacterization of the Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: potential for drug developmentDiversity of the biosynthesis pathway for threonylcarbamoyladenosine (t(6)A), a universal modification of tRNAStructure of 2C-methyl-D-erythritol 2,4- cyclodiphosphate synthase: an essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development.Biosynthesis of isoprenoids: Crystal structure of 4-diphosphocytidyl-2C-methyl-D-erythritol kinaseThe structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discoveryA Structure-Based Approach to Ligand Discovery for 2 C -Methyl- d -erythritol-2,4-cyclodiphosphate Synthase: A Target for Antimicrobial Therapy †Combining functional and structural genomics to sample the essential Burkholderia structomeDiscovery of Inhibitors of 4'-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial TherapyCrystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessmentPrioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosisIspE inhibitors identified by a combination of in silico and in vitro high-throughput screeningIsolation of the rstA gene as a multicopy suppressor of YjeE, an essential ATPase of unknown function in Escherichia coliExpression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens.Simple genetic selection protocol for isolation of overexpressed genes that enhance accumulation of membrane-integrated human G protein-coupled receptors in Escherichia coliA modular minimal cell model: purine and pyrimidine transport and metabolismFragment screening of infectious disease targets in a structural genomics environmentHorizontal transfer of drug-resistant aminoacyl-transfer-RNA synthetases of anthrax and Gram-positive pathogens.Investigating the predictability of essential genes across distantly related organisms using an integrative approachThe yjeQ gene is required for virulence of Staphylococcus aureusDprB facilitates inter- and intragenomic recombination in Helicobacter pyloriIdentification of novel virulence-associated genes via genome analysis of hypothetical genes.The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target.Essentiality of threonylcarbamoyladenosine (t(6)A), a universal tRNA modification, in bacteria.Conserved network of proteins essential for bacterial viabilitySequencing of bacterial genomes: principles and insights into pathogenesis and development of antibiotics.Is life unique?An array of Escherichia coli clones over-expressing essential proteins: a new strategy of identifying cellular targets of potent antibacterial compounds.Structure-Activity Relationships of the MEPicides: N-Acyl and O-Linked Analogs of FR900098 as Inhibitors of Dxr from Mycobacterium tuberculosis and Yersinia pestis.Deletion of lolB, encoding an outer membrane lipoprotein, is lethal for Escherichia coli and causes accumulation of lipoprotein localization intermediates in the periplasm.Characterization of the depletion of 2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase in Escherichia coli and Bacillus subtilis.The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli.Probing the active site of YjeE: a vital Escherichia coli protein of unknown function.Characterization of Helicobacter pylori factors that control transformation frequency and integration length during inter-strain DNA recombination.Phosphopantetheine adenylyltransferase from Escherichia coli: investigation of the kinetic mechanism and role in regulation of coenzyme A biosynthesis.Characterization of the Bacillus subtilis GTPase YloQ and its role in ribosome function.
P2860
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P2860
Identification of novel essential Escherichia coli genes conserved among pathogenic bacteria.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Identification of novel essent ...... ved among pathogenic bacteria.
@ast
Identification of novel essent ...... ved among pathogenic bacteria.
@en
type
label
Identification of novel essent ...... ved among pathogenic bacteria.
@ast
Identification of novel essent ...... ved among pathogenic bacteria.
@en
prefLabel
Identification of novel essent ...... ved among pathogenic bacteria.
@ast
Identification of novel essent ...... ved among pathogenic bacteria.
@en
P2093
P1476
Identification of novel essent ...... rved among pathogenic bacteria
@en
P2093
Freiberg C
Labischinski H
Spaltmann F
P304
P577
2001-07-01T00:00:00Z