3D structural model of the G-protein-coupled cannabinoid CB2 receptor.
about
Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligandsWhat we know and do not know about the cannabinoid receptor 2 (CB2)Understanding functional residues of the cannabinoid CB1.Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effectsA targeted library screen reveals a new inhibitor scaffold for protein kinase DLocation, structure, and dynamics of the synthetic cannabinoid ligand CP-55,940 in lipid bilayers.AlzPlatform: an Alzheimer's disease domain-specific chemogenomics knowledgebase for polypharmacology and target identification research.Difference and Influence of Inactive and Active States of Cannabinoid Receptor Subtype CB2: From Conformation to Drug Discovery.Comparative normal/failing rat myocardium cell membrane chromatographic analysis system for screening specific components that counteract doxorubicin-induced heart failure from Acontium carmichaeli.Endocannabinoid binding to the cannabinoid receptors: what is known and what remains unknown.Modeling, molecular dynamics simulation, and mutation validation for structure of cannabinoid receptor 2 based on known crystal structures of GPCRs.Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitorsEchinacea alkylamides modulate TNF-alpha gene expression via cannabinoid receptor CB2 and multiple signal transduction pathways.64Cu-labeled somatostatin analogues conjugated with cross-bridged phosphonate-based chelators via strain-promoted click chemistry for PET imaging: in silico through in vivo studiesTrisubstituted Sulfonamides: a New Chemotype for Development of Potent and Selective CB2 Receptor Inverse Agonists.Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists.Allosteric Binding Site and Activation Mechanism of Class C G-Protein Coupled Receptors: Metabotropic Glutamate Receptor Family.2,3-Dihydro-1-benzofuran derivatives as a series of potent selective cannabinoid receptor 2 agonists: design, synthesis, and binding mode prediction through ligand-steered modeling.Recombinant cannabinoid type 2 receptor in liposome model activates g protein in response to anionic lipid constituents.CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potencyStructural insight into tetrameric hTRPV1 from homology modeling, molecular docking, molecular dynamics simulation, virtual screening, and bioassay validations.Small-molecule inhibitors targeting INK4 protein p18(INK4C) enhance ex vivo expansion of haematopoietic stem cells.Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion.Mutagenesis and computer modeling studies of a GPCR conserved residue W5.43(194) in ligand recognition and signal transduction for CB2 receptor.Latest advances in novel cannabinoid CB(2) ligands for drug abuse and their therapeutic potential.The cannabinoid receptors are required for ultraviolet-induced inflammation and skin cancer developmentSolid-state NMR and molecular dynamics characterization of cannabinoid receptor-1 (CB1) helix 7 conformational plasticity in model membranesCardiovascular Disease Chemogenomics Knowledgebase-guided Target Identification and Drug Synergy Mechanism Study of an Herbal Formula.Lead discovery, chemistry optimization, and biological evaluation studies of novel biamide derivatives as CB2 receptor inverse agonists and osteoclast inhibitorsNovel triaryl sulfonamide derivatives as selective cannabinoid receptor 2 inverse agonists and osteoclast inhibitors: discovery, optimization, and biological evaluation.Cannabinoid receptor 2: potential role in immunomodulation and neuroinflammation.LiCABEDS II. Modeling of ligand selectivity for G-protein-coupled cannabinoid receptorsAdvances in methods to characterize ligand-induced ionic lock and rotamer toggle molecular switch in G protein-coupled receptorsMistic and TarCF as fusion protein partners for functional expression of the cannabinoid receptor 2 in Escherichia coli.StemCellCKB: An Integrated Stem Cell-Specific Chemogenomics KnowledgeBase for Target Identification and Systems-Pharmacology Research.Biosynthesis, purification, and characterization of a cannabinoid receptor 2 fragment (CB2(271-326)).p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis.Examining the critical roles of human CB2 receptor residues Valine 3.32 (113) and Leucine 5.41 (192) in ligand recognition and downstream signaling activitiesChemogenomics knowledgebase and systems pharmacology for hallucinogen target identification-Salvinorin A as a case study.NMR structural comparison of the cytoplasmic juxtamembrane domains of G-protein-coupled CB1 and CB2 receptors in membrane mimetic dodecylphosphocholine micelles.
P2860
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P2860
3D structural model of the G-protein-coupled cannabinoid CB2 receptor.
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
3D structural model of the G-protein-coupled cannabinoid CB2 receptor.
@ast
3D structural model of the G-protein-coupled cannabinoid CB2 receptor.
@en
type
label
3D structural model of the G-protein-coupled cannabinoid CB2 receptor.
@ast
3D structural model of the G-protein-coupled cannabinoid CB2 receptor.
@en
prefLabel
3D structural model of the G-protein-coupled cannabinoid CB2 receptor.
@ast
3D structural model of the G-protein-coupled cannabinoid CB2 receptor.
@en
P2093
P921
P356
P1433
P1476
3D structural model of the G-protein-coupled cannabinoid CB2 receptor.
@en
P2093
Eric M Billings
Jian-Zhong Chen
Xiang-Qun Xie
P304
P356
10.1002/PROT.10511
P407
P577
2003-11-01T00:00:00Z