Identification of the protein kinase A regulatory RIalpha-catalytic subunit interface by amide H/2H exchange and protein docking.
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Predicting Allosteric Effects from Orthosteric Binding in Hsp90-Ligand Interactions: Implications for Fragment-Based Drug DesignPeptide-column interactions and their influence on back exchange rates in hydrogen/deuterium exchange-MS.Data-driven docking for the study of biomolecular complexes.Exploring the interaction between the protein kinase A catalytic subunit and caveolin-1 scaffolding domain with shotgun scanning, oligomer complementation, NMR, and dockingAutomated extraction of backbone deuteration levels from amide H/2H mass spectrometry experiments.Structural mass spectrometry of the alpha beta-tubulin dimer supports a revised model of microtubule assemblyH/D exchange and mass spectrometry in the studies of protein conformation and dynamics: is there a need for a top-down approach?Protein docking prediction using predicted protein-protein interface.Active site coupling in PDE:PKA complexes promotes resetting of mammalian cAMP signaling.R-subunit isoform specificity in protein kinase A: distinct features of protein interfaces in PKA types I and II by amide H/2H exchange mass spectrometry.Folding and assembly of large macromolecular complexes monitored by hydrogen-deuterium exchange and mass spectrometry.A unique mode of microtubule stabilization induced by peloruside AApplication of hydrogen/deuterium exchange mass spectrometry to study protein tyrosine phosphatase dynamics, ligand binding, and substrate specificitySignaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design.Painting proteins with covalent labels: what's in the picture?Simulated Isotope Exchange Patterns Enable Protein Structure Determination.Hydrogen/deuterium exchange mass spectrometry and site-directed disulfide cross-linking suggest an important dynamic interface between the two lysostaphin domains.Hydrogen-Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling.A combined structural dynamics approach identifies a putative switch in factor VIIa employed by tissue factor to initiate blood coagulation.Structural analysis of diheme cytochrome c by hydrogen-deuterium exchange mass spectrometry and homology modelingProtein-protein interactions as a tool for site-specific labeling of proteins.Molecular Simulations Reveal an Unresolved Conformation of the Type IA Protein Kinase A Regulatory Subunit and Suggest Its Role in the cAMP Regulatory Mechanism.Application of amide proton exchange mass spectrometry for the study of protein-protein interactions.The conformationally dynamic C helix of the RIalpha subunit of protein kinase A mediates isoform-specific domain reorganization upon C subunit binding.Optimization of Feasibility Stage for Hydrogen/Deuterium Exchange Mass Spectrometry.An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery.C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change.On the use of distance constraints in protein-protein docking computations.Comparative thermodynamic analysis of cyclic nucleotide binding to protein kinase A
P2860
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P2860
Identification of the protein kinase A regulatory RIalpha-catalytic subunit interface by amide H/2H exchange and protein docking.
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Identification of the protein ...... exchange and protein docking.
@ast
Identification of the protein ...... exchange and protein docking.
@en
type
label
Identification of the protein ...... exchange and protein docking.
@ast
Identification of the protein ...... exchange and protein docking.
@en
prefLabel
Identification of the protein ...... exchange and protein docking.
@ast
Identification of the protein ...... exchange and protein docking.
@en
P2093
P2860
P356
P1476
Identification of the protein ...... exchange and protein docking.
@en
P2093
Aaron N Snead
Dennis Law
Elizabeth A Komives
Ganesh S Anand
Igor Tsigelny
Jeffrey G Mandell
Lynn F Ten Eyck
Susan S Taylor
P2860
P304
13264-13269
P356
10.1073/PNAS.2232255100
P407
P577
2003-10-28T00:00:00Z