C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change.
about
Assembly of allosteric macromolecular switches: lessons from PKAPKA Type II Holoenzyme Reveals a Combinatorial Strategy for Isoform DiversityRealizing the Allosteric Potential of the Tetrameric Protein Kinase A RIα HoloenzymeLocalization and quaternary structure of the PKA RI holoenzymeStructure and Allostery of the PKA RII Tetrameric HoloenzymeA dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinaseThe roles of the RIIβ linker and N-terminal cyclic nucleotide-binding domain in determining the unique structures of the type IIβ protein kinase A: a small angle x-ray and neutron scattering study.Normal Mode Flexible Fitting of High-Resolution Structures of Biological Molecules Toward SAXS DataNormal-mode flexible fitting of high-resolution structure of biological molecules toward one-dimensional low-resolution dataConformational changes in Sindbis virus induced by decreased pH are revealed by small-angle neutron scatteringEvolution of the eukaryotic protein kinases as dynamic molecular switches.New sources and instrumentation for neutrons in biology.Investigating the local flexibility of functional residues in hemoproteins.Discovery of Allostery in PKA Signaling.Neutron scattering techniques and applications in structural biology.Molecular Simulations Reveal an Unresolved Conformation of the Type IA Protein Kinase A Regulatory Subunit and Suggest Its Role in the cAMP Regulatory Mechanism.Structure of a PKA RIα Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation.The conformationally dynamic C helix of the RIalpha subunit of protein kinase A mediates isoform-specific domain reorganization upon C subunit binding.
P2860
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P2860
C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change.
description
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name
C subunits binding to the prot ...... a large conformational change.
@en
C subunits binding to the prot ...... a large conformational change.
@nl
type
label
C subunits binding to the prot ...... a large conformational change.
@en
C subunits binding to the prot ...... a large conformational change.
@nl
prefLabel
C subunits binding to the prot ...... a large conformational change.
@en
C subunits binding to the prot ...... a large conformational change.
@nl
P2860
P50
P356
P1476
C subunits binding to the prot ...... a large conformational change.
@en
P2093
Dominico Vigil
Susan S Taylor
P2860
P304
19084-19090
P356
10.1074/JBC.M313405200
P407
P577
2004-02-25T00:00:00Z