Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB.
about
Microevolution of group A streptococci in vivo: capturing regulatory networks engaged in sociomicrobiology, niche adaptation, and hypervirulencePhages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversionA novel endogenous inhibitor of the secreted streptococcal NAD-glycohydrolase.Genome-wide analysis of group a streptococci reveals a mutation that modulates global phenotype and disease specificity.Structure-Informed Design of an Enzymatically Inactive Vaccine Component for Group A StreptococcusDispersal of Group A streptococcal biofilms by the cysteine protease SpeB leads to increased disease severity in a murine modelA Two-Component Regulatory System Impacts Extracellular Membrane-Derived Vesicle Production in Group A StreptococcusTracing the evolutionary history of the pandemic group A streptococcal M1T1 clone.Novel algorithms reveal streptococcal transcriptomes and clues about undefined genesEndoS from Streptococcus pyogenes is hydrolyzed by the cysteine proteinase SpeB and requires glutamic acid 235 and tryptophans for IgG glycan-hydrolyzing activityAn unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis.A naturally occurring mutation in ropB suppresses SpeB expression and reduces M1T1 group A streptococcal systemic virulence.Clindamycin-induced CovS-mediated regulation of the production of virulent exoproteins streptolysin O, NAD glycohydrolase, and streptokinase in Streptococcus pyogenes.Wiring the streptococcal network for alternative lifestylesDifferences in SpeB protease activity among group A streptococci associated with superficial, invasive, and autoimmune disease.Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus.Surface analyses and immune reactivities of major cell wall-associated proteins of group a streptococcus.Impact of the SpeB protease on binding of the complement regulatory proteins factor H and factor H-like protein 1 by Streptococcus pyogenes.Genetic switch to hypervirulence reduces colonization phenotypes of the globally disseminated group A streptococcus M1T1 clone.Srv mediated dispersal of streptococcal biofilms through SpeB is observed in CovRS+ strainsM protein and hyaluronic acid capsule are essential for in vivo selection of covRS mutations characteristic of invasive serotype M1T1 group A Streptococcus.Comprehensive characterization of methicillin-resistant Staphylococcus aureus subsp. aureus COL secretome by two-dimensional liquid chromatography and mass spectrometry.Group A Streptococcus secreted esterase hydrolyzes platelet-activating factor to impede neutrophil recruitment and facilitate innate immune evasionCysteine proteinase SpeB from Streptococcus pyogenes - a potent modifier of immunologically important host and bacterial proteins.CodY-mediated regulation of Streptococcus pyogenes exoproteins.Staphylococcal and streptococcal superantigen exotoxinsGenome-wide identification of genes required for fitness of group A Streptococcus in human bloodPartial loss of CovS function in Streptococcus pyogenes causes severe invasive diseaseNaturally occurring single amino acid replacements in a regulatory protein alter streptococcal gene expression and virulence in mice.The Streptococcus pyogenes proteome: maps, virulence factors and vaccine candidates.Streptococcal SpeB cleaved PAR-1 suppresses ERK phosphorylation and blunts thrombin-induced platelet aggregation.Group A Streptococcus transcriptome dynamics during growth in human blood reveals bacterial adaptive and survival strategies.Characterization of the effect of the histidine kinase CovS on response regulator phosphorylation in group A Streptococcus.Mutations in the control of virulence sensor gene from Streptococcus pyogenes after infection in mice lead to clonal bacterial variants with altered gene regulatory activity and virulence.Adhesin degradation accelerates delivery of heat-labile toxin by enterotoxigenic Escherichia coliStreptococcal inhibitor of complement promotes innate immune resistance phenotypes of invasive M1T1 group A StreptococcusParameters governing invasive disease propensity of non-M1 serotype group A streptococci.Genetic characterization and virulence role of the RALP3/LSA locus upstream of the streptolysin s operon in invasive M1T1 Group A Streptococcus.Serotype M3 and M28 Group A Streptococci Have Distinct Capacities to Evade Neutrophil and TNF-α Responses and to Invade Soft Tissues.A group A Streptococcus ADP-ribosyltransferase toxin stimulates a protective interleukin 1β-dependent macrophage immune response
P2860
Q21142618-61356823-FC50-4E5F-9DB4-A33A9AB298E9Q24562822-1DC0601C-B472-47BA-AD7C-C769166B3034Q24814657-2BE90E16-34C5-4CF5-937B-78C3503B5BA2Q25257695-AE291C3C-0CDB-4BBB-88F2-A03C016CC8AFQ27679389-173A6F5B-4133-49BE-A943-FCE19842EB68Q28477890-6EF83DE9-9EB0-4DC9-9F85-7C73E2191C92Q29114103-B1F491E4-B699-459E-9814-CA2BA3B335ECQ30420207-87220014-C2D0-4D2B-A8D5-D503B0C483DDQ33290226-B05A45B8-CF3E-42DB-8108-B714B2CDD11CQ33313641-03F91B08-5262-4903-99D7-C2B82942F416Q33329093-A2D9A7C1-812B-4661-BE7E-4808972B37C7Q33396665-D3589513-F190-432B-A6D9-39F4CC0B77D2Q33558911-903473A0-24AC-4635-B325-247A62118555Q33678838-8F315597-5CE9-419B-9E95-97C5155D63EDQ33699090-70AA200F-BB83-47DF-A99E-C9568E4E2B5AQ33729992-D7CDF25C-DE0E-4242-A582-2FFF1CA5F483Q33769155-63402371-496A-45B6-A362-E4A458E955EFQ33769440-A7C0D90B-56C3-4EB1-A5E2-7DD690C9B539Q33893802-3011FFD6-0FDF-4283-8CF5-2BE4136B7363Q34098283-3EE78EC6-65BF-49F8-B54B-98B51C3FD264Q34107122-CFC055A9-02E6-41B7-BC7A-576418BC7005Q34122234-48BCC354-5674-4D2A-8CEA-8495062B776DQ34229649-00EC8C69-F24E-4D88-A0A6-B29FBEE69D72Q34229809-5E8E58D7-9861-4FF6-AF95-166DD6AFF1CEQ34313023-C4A489EA-9180-4CF5-B409-88D3C80603FDQ34355243-420AA0B6-C341-4AC4-98DB-7CA8AA70A0C0Q34538936-36C7261C-F127-4AA0-BF0D-1F3860972F51Q34640704-B9FA7099-38A5-41A3-8028-178068502374Q34876077-E1FDC326-37F3-43FE-A2B1-38297468E91AQ34974840-6E087F64-C1FD-483C-BF9A-A2B482C52B05Q35053984-66DAEA5F-A830-4766-AB03-EC388917B356Q35083669-8C3AAC01-A3F3-4BDF-93D4-D3230AFC3E33Q35098229-43E2FD88-4C42-4298-8E31-DA3E39E325B8Q35195790-7CB02E16-4711-4D93-A20F-57B6EF8E1C29Q35313799-E3BF8BD0-03BF-4D75-B923-35F00DA39BE0Q35559866-E84F5470-2E9E-4187-98DD-3F3B0CA269F6Q35559870-53643DB8-B3A3-4DEC-833B-F4C13E110584Q35634671-3DFAE43B-F65E-4D3B-9397-0C5FBCA8B2E3Q35654539-623A9E6F-0394-4EB9-B7B8-F18FF3A2B0A7Q35677468-C9ECD304-E4CA-476F-9697-0E35DC971831
P2860
Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Invasive M1T1 group A Streptoc ...... ple virulence factors by SpeB.
@ast
Invasive M1T1 group A Streptoc ...... ple virulence factors by SpeB.
@en
type
label
Invasive M1T1 group A Streptoc ...... ple virulence factors by SpeB.
@ast
Invasive M1T1 group A Streptoc ...... ple virulence factors by SpeB.
@en
prefLabel
Invasive M1T1 group A Streptoc ...... ple virulence factors by SpeB.
@ast
Invasive M1T1 group A Streptoc ...... ple virulence factors by SpeB.
@en
P2093
P50
P1476
Invasive M1T1 group A Streptoc ...... ple virulence factors by SpeB.
@en
P2093
Arthur Jeng
Malak Kotb
Michael J Pabst
Rita Kansal
P304
P356
10.1046/J.1365-2958.2003.03797.X
P407
P577
2004-01-01T00:00:00Z