The human telomerase gene: complete genomic sequence and analysis of tandem repeat polymorphisms in intronic regions.
about
Human telomerase and its regulationA general cloning system to selectively isolate any eukaryotic or prokaryotic genomic region in yeastVariation at the TERT locus and predisposition for cancerOptimum conditions for selective isolation of genes from complex genomes by transformation-associated recombination cloning.Segments missing from the draft human genome sequence can be isolated by transformation-associated recombination cloning in yeast.Closing the gaps on human chromosome 19 revealed genes with a high density of repetitive tandemly arrayed elements.Rare exonic minisatellite alleles in MUC2 influence susceptibility to gastric carcinoma.Short rare hTERT-VNTR2-2nd alleles are associated with prostate cancer susceptibility and influence gene expression.Ancestral mutation in telomerase causes defects in repeat addition processivity and manifests as familial pulmonary fibrosis.Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repressionDifferential cis-regulation of human versus mouse TERT gene expression in vivo: identification of a human-specific repressive element.Association between hTERT polymorphisms and the risk of breast cancer in a sample of Southeast Iranian population.Highly efficient CRISPR/Cas9-mediated TAR cloning of genes and chromosomal loci from complex genomes in yeast.Regulation of hTERT transcription: a target of cellular and viral mechanisms for immortalization and carcinogenesis.TAR cloning: insights into gene function, long-range haplotypes and genome structure and evolution.Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p- syndrome.Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing.Structure-function relationships in telomerase genes.The GG genotype of telomerase reverse transcriptase at genetic locus rs2736100 is associated with human atherosclerosis risk in the Han Chinese population.Regulation of human telomerase splicing by RNA:RNA pairing.Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration.Transformation-associated recombination (TAR) cloning for genomics studies and synthetic biology.Regulation of telomerase alternative splicing: a target for chemotherapyAssociation of MUC6-minisatellite variants with susceptibility to rectal carcinoma.Alternative splicing of human telomerase reverse transcriptase in gliomas and its modulation mediated by CX-5461.The role of human telomerase catalytic subunit mRNA expression in cervical dysplasias.Telomerase reverse transcriptase gene amplification in hepatocellular carcinoma.
P2860
Q24533247-E570E42A-1F6E-4993-9662-F106CE11E406Q24799426-4571027C-DB2E-44E4-951F-BD53808D561AQ28282704-765C742C-B1A2-4F84-B331-EB178F8A9275Q30894014-F49467A6-1A84-42FD-B1EF-02AB96A18E28Q30896497-4C34CB2A-5BEC-4790-AE89-51647A9E45F0Q33196739-EE3C4BB7-3EB2-4530-BDBE-9BE3E2D6FDC9Q33305433-D5C9195E-A6FA-4D0B-9E88-FD7163850A72Q33640732-C3F64486-E76D-4E0D-B2AE-A892BE7F3EAAQ33869660-C84E4646-1A5C-431E-81BF-B5449D37EBFBQ33902802-AF2E9CB0-2DCC-472E-9070-E3B38E801D8BQ34234726-CA3CEE8A-CFD1-4D0D-A67D-3ACDB3FE79F2Q34967865-BC0F8486-71BB-4028-813C-E8F84B8BB828Q35562036-36D2428A-4ECC-4AB4-BB23-A1515F088349Q36255506-4383D975-D6E6-429E-BB68-5EAE2B9877A6Q36597332-DA889166-FFE3-4057-A9C4-4F32A8A1C6F5Q36973951-769F3D2D-D0A8-4E73-AA17-700CD6241A34Q37068421-45DB62F3-9607-493A-A9AC-12B1F8D8BBF6Q37472153-BBDDC1D4-0B00-4235-B9C6-C20A62926CF3Q37499624-FAD3F176-2CE2-49DE-BF94-50AA50506726Q37627827-84C2EAF5-1526-4D57-A51D-78B290041EDCQ38349636-AE4DC14C-4BBF-48FC-929E-CFA55499D546Q38817999-33F924FF-B9E8-4EB6-A961-C4B4D99F2E6FQ39170483-8A8F0801-6900-4CC2-B1D6-E928C4E61126Q51304519-ABE02028-8243-466B-8035-543083DC6C65Q52598196-3AA0C066-F4F1-49A8-A2EA-007D3578578AQ54673771-1375CCC4-750D-4C67-B5B7-5129002C8F85Q54697555-C7851635-D278-4306-92A9-912902749A7D
P2860
The human telomerase gene: complete genomic sequence and analysis of tandem repeat polymorphisms in intronic regions.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The human telomerase gene: com ...... morphisms in intronic regions.
@ast
The human telomerase gene: com ...... morphisms in intronic regions.
@en
type
label
The human telomerase gene: com ...... morphisms in intronic regions.
@ast
The human telomerase gene: com ...... morphisms in intronic regions.
@en
prefLabel
The human telomerase gene: com ...... morphisms in intronic regions.
@ast
The human telomerase gene: com ...... morphisms in intronic regions.
@en
P2093
P2860
P356
P1433
P1476
The human telomerase gene: com ...... morphisms in intronic regions.
@en
P2093
Emmanuel Tubacher
Greg Solomon
Izumi Horikawa
J Arturo Londoño-Vallejo
J Carl Barrett
Jung-Eun Park
Jung-Hyun Kim
Natalay Kouprina
Sun-Hee Leem
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205122
P407
P577
2002-01-01T00:00:00Z
P5875
P6179
1016051094