Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration.
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Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescenceThermodynamic characterization of binding Oxytricha nova single strand telomere DNA with the alpha protein N-terminal domain.Tomentosin Induces Telomere Shortening and Caspase-Dependant Apoptosis in Cervical Cancer Cells.Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells.Targeting human telomerase for cancer therapeutics.Fluorescence-based duplex-quadruplex competition test to screen for telomerase RNA quadruplex ligandsStructural insights into G-quadruplexes: towards new anticancer drugs.A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells.Telomeres, telomerase, and apoptosis.Mechanism of the antiproliferative activity of some naphthalene diimide G-quadruplex ligands.Proteome alteration induced by hTERT transfection of human fibroblast cells.DNA damage signaling induced by the G-quadruplex ligand 12459 is modulated by PPM1D/WIP1 phosphatase.Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing.A hitchhiker's guide to G-quadruplex ligands.Experimental approaches to identify cellular G-quadruplex structures and functions.G-quadruplex interacting small molecules and drugs: from bench toward bedside.Inula Viscosa Extracts Induces Telomere Shortening and Apoptosis in Cancer Cells and Overcome Drug Resistance.Telomerase and drug resistance in cancer.Interaction of TMPyP4, TMPyP3, and TMPyP2 with Intramolecular G-Quadruplex Formed by Promoter Region of Bcl2 and KRAS NHPPE
P2860
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P2860
Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Resistance to the short term a ...... d telomere capping alteration.
@en
type
label
Resistance to the short term a ...... d telomere capping alteration.
@en
prefLabel
Resistance to the short term a ...... d telomere capping alteration.
@en
P2093
P2860
P356
P1476
Resistance to the short term a ...... d telomere capping alteration.
@en
P2093
Chantal Trentesaux
Céline Douarre
Dennis Gomez
Frédérique Mégnin-Chanet
Hamid Morjani
Jean-François Riou
Kazuo Shin-ya
Laurent Lacroix
Nassera Aouali
Patrick Mailliet
P2860
P304
50554-50562
P356
10.1074/JBC.M308440200
P407
P577
2003-10-02T00:00:00Z