Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene
about
ABC transporters: bacterial exportersPhysiological consequences of drug resistance in Leishmania and their relevance for chemotherapyFormation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania.Identification of Saccharomyces cerevisiae genes conferring resistance to quinoline ring-containing antimalarial drugsEfficacy of the herbicide trifluralin against four P-glycoprotein-expressing strains of LeishmaniaRole of efflux pumps and intracellular thiols in natural antimony resistant isolates of Leishmania donovaniDrug resistance in natural isolates of Leishmania donovani s.l. promastigotes is dependent of Pgp170 expressionCase Report: No Response to Liposomal Daunorubicin in a Patient with Drug-Resistant HIV-Associated Visceral LeishmaniasisCharacterization of a Novel Endoplasmic Reticulum Protein Involved in Tubercidin Resistance in Leishmania majorIsolation of genes mediating resistance to inhibitors of nucleoside and ergosterol metabolism in Leishmania by overexpression/selection.Cloning and heterologous expression of the ovine (Ovis aries) P-glycoprotein (Mdr1) in Madin-Darby canine kidney (MDCK) cells.High-affinity binding of silybin derivatives to the nucleotide-binding domain of a Leishmania tropica P-glycoprotein-like transporter and chemosensitization of a multidrug-resistant parasite to daunomycin.Frequency of drug resistance gene amplification in clinical leishmania strainsCombination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug effluxModulation of Leishmania ABC protein gene expression through life stages and among drug-resistant parasites.Antimony resistance in leishmania, focusing on experimental research.P-glycoprotein structure and evolutionary homologies.Unstable amplification of two extrachromosomal elements in alpha-difluoromethylornithine-resistant Leishmania donovani.Geographical Distribution of MDR1 Expression in Leishmania Isolates, from Greece and Cyprus, Measured by the Rhodamine-123 Efflux Potential of the Isolates, Using Flow Cytometry.Inhibition of growth of Leishmania donovani promastigotes by newly synthesized 1,3,4-thiadiazole analogs.The Role of Signaling via Aqueous Pore Formation in Resistance Responses to Amphotericin BIdentification and Characterization of miRNAs in Response to Leishmania donovani Infection: Delineation of Their Roles in Macrophage DysfunctionDrug resistance in leishmaniasis: current drug-delivery systems and future perspectives.Identification and chromosomal localization of one locus of Leishmania (L.) major related with resistance to itraconazole.Susceptibility of an emetine-resistant mutant of Entamoeba histolytica to multiple drugs and to channel blockers.Mechanism of amphotericin B resistance in clinical isolates of Leishmania donovaniAlkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulatorThe Leishmania genome comprises 36 chromosomes conserved across widely divergent human pathogenic species.Detection of drug resistance gene in cutaneous leishmaniasis by PCR in some endemic areas of iran.Homologous recombination between direct repeat sequences yields P-glycoprotein containing amplicons in arsenite resistant Leishmania.Multidrug resistance and P-glycoproteins in parasitic protozoa.Localization and activity of multidrug resistance protein 1 in the secretory pathway of Leishmania parasites.A New Antileishmanial Preparation of Combined Solamargine and Solasonine Heals Cutaneous Leishmaniasis through Different Immunochemical Pathways.MAPK1 of Leishmania donovani modulates antimony susceptibility by downregulating P-glycoprotein efflux pumps.A new type of hazardous chemical: the chemosensitizers of multixenobiotic resistance.Flavonoid dimers as bivalent modulators for pentamidine and sodium stiboglucanate resistance in leishmania.Identification of an ABC transporter gene that exhibits mRNA level overexpression in fluoroquinolone-resistant Mycobacterium smegmatis.Cell structure and cytokinesis alterations in multidrug-resistant Leishmania (Leishmania) amazonensis.Evidence that phosphate specific transporter is amplified in a fluoroquinolone resistant Mycobacterium smegmatis.Identification of a multidrug resistance-like system in Tetrahymena pyriformis: evidence for a new detoxication mechanism in freshwater ciliates.
P2860
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P2860
Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene
description
1992 nî lūn-bûn
@nan
1992 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Multidrug resistance in Leishm ...... ous to the mammalian mdr1 gene
@ast
Multidrug resistance in Leishm ...... ous to the mammalian mdr1 gene
@en
type
label
Multidrug resistance in Leishm ...... ous to the mammalian mdr1 gene
@ast
Multidrug resistance in Leishm ...... ous to the mammalian mdr1 gene
@en
prefLabel
Multidrug resistance in Leishm ...... ous to the mammalian mdr1 gene
@ast
Multidrug resistance in Leishm ...... ous to the mammalian mdr1 gene
@en
P2093
P2860
P356
P1476
Multidrug resistance in Leishm ...... ous to the mammalian mdr1 gene
@en
P2093
D M Henderson
N Hendrickson
P2860
P304
P356
10.1128/MCB.12.6.2855
P407
P577
1992-06-01T00:00:00Z