about
Engineered IgG1-Fc--one fragment to bind them allHigh-affinity single-domain binding proteins with a binary-code interfaceStructural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'Exploring the Capacity of Minimalist Protein Interfaces: Interface Energetics and Affinity Maturation to Picomolar KD of a Single-domain Antibody with a Flat ParatopeSynthetic antibodies for specific recognition and crystallization of structured RNAA Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein–Protein InterfacesA potent and highly specific FN3 monobody inhibitor of the Abl SH2 domainStructural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrRChemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallographyCDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic AntibodiesStructure of human cytomegalovirus UL141 binding to TRAIL-R2 reveals novel, non-canonical death receptor interactionsSynthetic approach to the generation of antibody diversityEngineering of recombinant crystallization chaperonesThermodynamic additivity of sequence variations: an algorithm for creating high affinity peptides without large libraries or structural informationDirected Chemical Evolution with an Outsized Genetic CodeThermodynamics of antibody-antigen interaction revealed by mutation analysis of antibody variable regions.Structural analysis of B-cell epitopes in antibody:protein complexesAlternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis.Antibody binding loop insertions as diversity elementsIsolation of intracellular proteinase inhibitors derived from designed ankyrin repeat proteins by genetic screening.Synthetic antibodies as therapeutics.Amino acid alphabet size in protein evolution experiments: better to search a small library thoroughly or a large library sparsely?Two-state selection of conformation-specific antibodiesOverview on concepts and applications of Fab antibody fragments.The importance of being tyrosine: lessons in molecular recognition from minimalist synthetic binding proteins.The full amino acid repertoire is superior to serine/tyrosine for selection of high affinity immunoglobulin G binders from the fibronectin scaffoldHuman monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism.Protein-protein interactions and selection: generation of molecule-binding proteins on the basis of tertiary structural information.Discovery of high-affinity protein binding ligands--backwards.Mining human antibody repertoires.Contribution of light chain residues to high affinity binding in an HIV-1 antibody explored by combinatorial scanning mutagenesisStability and CDR composition biases enrich binder functionality landscapes.Monobodies and other synthetic binding proteins for expanding protein scienceEngineering a protein-protein interface using a computationally designed libraryAdnectins: engineered target-binding protein therapeuticsA portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination.Generation of recombinant guinea pig antibody fragments to the human GABAC receptor.Transthyretin-derived peptides as β-amyloid inhibitors.Synthetic Fab fragments that bind the HIV-1 gp41 heptad repeat regions.Crystal structure of an RNA polymerase ribozyme in complex with an antibody fragment.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Molecular recognition by a binary code.
@ast
Molecular recognition by a binary code.
@en
type
label
Molecular recognition by a binary code.
@ast
Molecular recognition by a binary code.
@en
prefLabel
Molecular recognition by a binary code.
@ast
Molecular recognition by a binary code.
@en
P2093
P1476
Molecular recognition by a binary code.
@en
P2093
Andrew A Peden
Deanne M Compaan
Frederic A Fellouse
Sachdev S Sidhu
Sarah G Hymowitz
P304
P356
10.1016/J.JMB.2005.03.041
P407
P577
2005-04-01T00:00:00Z