Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment.
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Effects of nicotine exposure on in vitro metabolism of chlorpyrifos in male Sprague-Dawley ratsPhenobarbital increases monkey in vivo nicotine disposition and induces liver and brain CYP2B6 proteinPathophysiological implications of neurovascular P450 in brain disordersEndocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibitionCytochrome P450-mediated drug metabolism in the brainDefective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C DiseaseChronic nicotine treatment induces rat CYP2D in the brain but not in the liver: an investigation of induction and time courseThe effect of aspartame on rat brain xenobiotic-metabolizing enzymesIn vivo investigation of brain and systemic ketobemidone metabolism.Regional and cellular expression of CYP2D6 in human brain: higher levels in alcoholics.Drug-metabolizing cytochrome P450s in the brain.Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics.Cytochrome P450 enzymes in the brain: emerging evidence of biological significanceThe unique regulation of brain cytochrome P450 2 (CYP2) family enzymes by drugs and genetics.An LC-MS/MS method for concurrent determination of nicotine metabolites and the role of CYP2A6 in nicotine metabolite-mediated oxidative stress in SVGA astrocytes.Subacute nicotine co-exposure has no effect on 2,2',3,5',6- pentachlorobiphenyl disposition but alters hepatic cytochrome P450 expression in the male rat.Nicotine regulates the expression of UDP-glucuronosyltransferase (UGT) in humanized UGT1 mouse brain.First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo.Age-related differences in the disposition of nicotine and metabolites in rat brain and plasma.ABC transporters and cytochromes P450 in the human central nervous system: influence on brain pharmacokinetics and contribution to neurodegenerative disorders.Emerging roles for brain drug-metabolizing cytochrome P450 enzymes in neuropsychiatric conditions and responses to drugs.Effect of Brain CYP2B Inhibition on Brain Nicotine Levels and Nicotine Self-Administration.Brain drug-metabolizing cytochrome P450 enzymes are active in vivo, demonstrated by mechanism-based enzyme inhibition.Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake.Role of cytochrome P450-dependent monooxygenases and polymorphic variants of GSTT1 and GSTM1 genes in the formation of brain lesions in individuals chronically exposed to mercury.Postnatal expression of cytochrome P450 1A1, 2A3, and 2B1 mRNA in neonatal rat lung: influence of maternal nicotine exposure.Metabolism of nicotine in rat lung microvascular endothelial cells.Cytochrome P450 expression in mouse brain: specific isoenzymes involved in Phase I metabolizing system of porphyrinogenic agents in both microsomes and mitochondria.Brain CYP2B induction can decrease nicotine levels in the brain.Expression and localization of the CYP2B subfamily predominantly in neurones of rat brain.Substituted heteroaromatic compounds: effect on nicotine self-administration in rats.Effect of Nicotine on CYP2B1 Expression in a Glioma Animal Model and Analysis of CYP2B6 Expression in Pediatric Gliomas.Extrahepatic Drug-Metabolizing Enzymes and Their Significance
P2860
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P2860
Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment.
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Regional and cellular inductio ...... by chronic nicotine treatment.
@ast
Regional and cellular inductio ...... by chronic nicotine treatment.
@en
type
label
Regional and cellular inductio ...... by chronic nicotine treatment.
@ast
Regional and cellular inductio ...... by chronic nicotine treatment.
@en
prefLabel
Regional and cellular inductio ...... by chronic nicotine treatment.
@ast
Regional and cellular inductio ...... by chronic nicotine treatment.
@en
P2093
P1476
Regional and cellular inductio ...... by chronic nicotine treatment.
@en
P2093
P304
P356
10.1016/S0006-2952(00)00281-1
P407
P577
2000-06-01T00:00:00Z