Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.
about
Targeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsKinase inhibitors from marine spongesAnalysing the Effect of Mutation on Protein Function and Discovering Potential Inhibitors of CDK4: Molecular Modelling and Dynamics StudiesQ28831186p42/p44 MAPKs are intracellular targets of the CDK inhibitor purvalanol.The identification of unique serum proteins of HIV-1 latently infected long-term non-progressor patients.Bioactive marine drugs and marine biomaterials for brain diseasesCyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progressionRegulation of glioblastoma progression by cord blood stem cells is mediated by downregulation of cyclin D1.Mechanism targeted discovery of antitumor marine natural products.Discovery of indolotryptoline antiproliferative agents by homology-guided metagenomic screening.Cyclin-dependent protein kinases as therapeutic drug targets for antimalarial drug development.Marine bioactives as functional food ingredients: potential to reduce the incidence of chronic diseasesA new paradigm for the development of anticancer agents from natural productsLimited redundancy in phosphorylation of retinoblastoma tumor suppressor protein by cyclin-dependent kinases in acute lymphoblastic leukemia3-bromohomofascaplysin A, a fascaplysin analogue from a Fijian Didemnum sp. ascidianSmall-molecule cyclin-dependent kinase modulators.Kinase inhibitor screening identifies CDK4 as a potential therapeutic target for melanomaThe Marine-Derived Kinase Inhibitor Fascaplysin Exerts Anti-Thrombotic ActivityFive years of progress on cyclin-dependent kinases and other cellular proteins as potential targets for antiviral drugs.Nuclear factor of activated T cells c1 mediates p21-activated kinase 1 activation in the modulation of chemokine-induced human aortic smooth muscle cell F-actin stress fiber formation, migration, and proliferation and injury-induced vascular wall reCytotoxic effects of fascaplysin against small cell lung cancer cell lines.Investigations of the marine flora and fauna of the Fiji Islands.Finding chemo: the search for marine-based pharmaceutical drugs active against cancer.Natural products from marine organisms with neuroprotective activity in the experimental models of Alzheimer's disease, Parkinson's disease and ischemic brain stroke: their molecular targets and action mechanisms.Marine Sponges and Bacteria as Challenging Sources of Enzyme Inhibitors for Pharmacological Applications.Effects of biodegradable Mg-6Zn alloy extracts on cell cycle of intestinal epithelial cells.The fate of pancreatic tumor cell lines following p16 overexpression depends on the modulation of CDK2 activity.Cell cycle and biochemical effects of PD 0183812. A potent inhibitor of the cyclin D-dependent kinases CDK4 and CDK6.New fascaplysin-based CDK4-specific inhibitors: design, synthesis and biological activity.Fascaplysin Exerts Anti-Cancer Effects through the Downregulation of Survivin and HIF-1α and Inhibition of VEGFR2 and TRKA.Sponges: A Reservoir of Genes Implicated in Human Cancer.Fascaplysin Sensitizes Anti-Cancer Effects of Drugs Targeting AKT and AMPK.EphB4 Regulates Self-Renewal, Proliferation and Neuronal Differentiation of Human Embryonic Neural Stem Cells in Vitro.Fascaplysin induces caspase mediated crosstalk between apoptosis and autophagy through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL-60 cells.Molecular Targets of Active Anticancer Compounds Derived from Marine Sources.
P2860
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P2860
Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.
description
2000 nî lūn-bûn
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2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.
@ast
Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.
@en
type
label
Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.
@ast
Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.
@en
prefLabel
Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.
@ast
Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.
@en
P2093
P356
P1476
Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.
@en
P2093
Chaudhuri B
Schoepfer J
Zumstein-Mecker S
P304
P356
10.1006/BBRC.2000.3349
P407
P577
2000-09-01T00:00:00Z