A genetic screen to identify genes that rescue the slow growth phenotype of c-myc null fibroblasts.
about
AP4 encodes a c-MYC-inducible repressor of p21c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cellsMyc/Max/Mad regulate the frequency but not the duration of productive cell cyclesA novel myc target gene, mina53, that is involved in cell proliferationThe oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entryA functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolismc-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolismA senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling.A functional genetic screen identifies TFE3 as a gene that confers resistance to the anti-proliferative effects of the retinoblastoma protein and transforming growth factor-beta.Disentangling the MYC web.Myc, mondo, and metabolismTargeting c-Myc as a novel approach for hepatocellular carcinoma.Loss of protooncogene c-Myc function impedes G1 phase progression both before and after the restriction pointN-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar developmentMyc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression.A MEK/PI3K/HDAC inhibitor combination therapy for KRAS mutant pancreatic cancer cells.Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.AP4 is required for mitogen- and c-MYC-induced cell cycle progression.Novel retroviral vectors to facilitate expression screens in mammalian cells.Myc down-regulation as a mechanism to activate the Rb pathway in STAT5A-induced senescence.Myc confers androgen-independent prostate cancer cell growth.N-Myc overexpression increases cisplatin resistance in neuroblastoma via deregulation of mitochondrial dynamics.AP4 directly downregulates p16 and p21 to suppress senescence and mediate transformation.MYC activity is negatively regulated by a C-terminal lysine cluster.Involvement of p53 in phthalate effects on mouse and rat osteoblasts.Analysis of genomic targets reveals complex functions of MYC.Defining the specific physiological requirements for c-Myc in T cell development.p27kip1-independent cell cycle regulation by MYC.Using myc genes to search for stem cells in the ciliary margin of the Xenopus retina.Regulation of calpain activity by c-Myc through calpastatin and promotion of transformation in c-Myc-negative cells by calpastatin suppression.
P2860
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P2860
A genetic screen to identify genes that rescue the slow growth phenotype of c-myc null fibroblasts.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
A genetic screen to identify g ...... ype of c-myc null fibroblasts.
@ast
A genetic screen to identify g ...... ype of c-myc null fibroblasts.
@en
type
label
A genetic screen to identify g ...... ype of c-myc null fibroblasts.
@ast
A genetic screen to identify g ...... ype of c-myc null fibroblasts.
@en
prefLabel
A genetic screen to identify g ...... ype of c-myc null fibroblasts.
@ast
A genetic screen to identify g ...... ype of c-myc null fibroblasts.
@en
P2093
P2860
P356
P1433
P1476
A genetic screen to identify g ...... ype of c-myc null fibroblasts.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203639
P407
P577
2000-07-01T00:00:00Z
P5875
P6179
1045257215