Defining the specific physiological requirements for c-Myc in T cell development.
about
myc maintains embryonic stem cell pluripotency and self-renewalGenomic targets of the human c-Myc proteinMetabolic regulation of T cell differentiation and functionN-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiationThe protooncogene MYC can break B cell toleranceTLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells.The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centersEpigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibilityNotch dimerization is required for leukemogenesis and T-cell development.A critical role for Mnt in Myc-driven T-cell proliferation and oncogenesisInflammatory disease and lymphomagenesis caused by deletion of the Myc antagonist Mnt in T cells.c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.Myc roles in hematopoiesis and leukemiaDifferential requirements for c-Myc in chronic hematopoietic hyperplasia and acute hematopoietic malignancies in Pten-null mice.Interactions between Ras1, dMyc, and dPI3K signaling in the developing Drosophila wing.Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network.HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRβ-selected mouse thymocytes.Co-targeting of Akt and Myc inhibits viability of lymphoma cells from Lck-Dlx5 mice.Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis.Distinct TCR signaling pathways drive proliferation and cytokine production in T cellsB-cell receptor signaling in the genesis and maintenance of B-cell lymphoma.Intrathymic proliferation wave essential for Valpha14+ natural killer T cell development depends on c-Myc.Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells.c-Myc-Induced Survivin Is Essential for Promoting the Notch-Dependent T Cell Differentiation from Hematopoietic Stem Cells.Transcription factors and target genes of pre-TCR signaling.Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1.GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fateT cell Myc-tabolism.c-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors.Global DNA methylation remodeling accompanies CD8 T cell effector function.Productive coupling of accessible Vbeta14 segments and DJbeta complexes determines the frequency of Vbeta14 rearrangement.c-Myc mediates pre-TCR-induced proliferation but not developmental progressionPathogenesis and therapeutic targeting of aberrant MYC expression in haematological cancers.Microarray transcript profiling distinguishes the transient from the acute type of megakaryoblastic leukaemia (M7) in Down's syndrome, revealing PRAME as a specific discriminating marker.BPTF Is Essential for T Cell Homeostasis and Function.Metabolic Regulation of T Cell Immunity.
P2860
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P2860
Defining the specific physiological requirements for c-Myc in T cell development.
description
2001 nî lūn-bûn
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2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Defining the specific physiological requirements for c-Myc in T cell development.
@en
Defining the specific physiological requirements for c-Myc in T cell development.
@nl
type
label
Defining the specific physiological requirements for c-Myc in T cell development.
@en
Defining the specific physiological requirements for c-Myc in T cell development.
@nl
prefLabel
Defining the specific physiological requirements for c-Myc in T cell development.
@en
Defining the specific physiological requirements for c-Myc in T cell development.
@nl
P2093
P2860
P356
P1433
P1476
Defining the specific physiological requirements for c-Myc in T cell development.
@en
P2093
P2860
P304
P356
10.1038/86308
P407
P577
2001-04-01T00:00:00Z