Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints. - Wikidata - awgldk - TriplyDB

Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.

Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.

http://www.wikidata.org/entity/Q31914935

about

Inhibition of mutation and combating the evolution of antibiotic resistance Induction of unique structural changes in guanine-rich DNA regions by the triazoloacridone C-1305, a topoisomerase II inhibitor with antitumor activities.Molecular mechanisms of etoposide Molecular and Pharmacologic Properties of the Anticancer Quinolone Derivative Vosaroxin: A New Therapeutic Agent for Acute Myeloid Leukemia Myeloperoxidase Enhances Etoposide and Mitoxantrone-Mediated DNA Damage: A Target for Myeloprotection in Cancer Chemotherapy Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation Molecular analysis of t(15;17) genomic breakpoints in secondary acute promyelocytic leukemia arising after treatment of multiple sclerosis Leukemias related to treatment with DNA topoisomerase II inhibitors.Catalytic core of human topoisomerase IIα: insights into enzyme-DNA interactions and drug mechanism Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides A novel selection system for chromosome translocations in Saccharomyces cerevisiae.Myeloperoxidase-dependent oxidation of etoposide in human myeloid progenitor CD34+ cells Acidic pH induces topoisomerase II-mediated DNA damage.Etoposide quinone is a redox-dependent topoisomerase II poison Second cancers in survivors of childhood cancer.Molecular pathogenesis of secondary acute promyelocytic leukemia Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.Secondary leukemia associated with the anti-cancer agent, etoposide, a topoisomerase II inhibitor Position-specific trapping of topoisomerase II by benzo[a]pyrene diol epoxide adducts: implications for interactions with intercalating anticancer agents.Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome Iron chelators with topoisomerase-inhibitory activity and their anticancer applications.DNA topoisomerase II, genotoxicity, and cancer Role of nitric oxide in the chemistry and anticancer activity of etoposide (VP-16,213).Influence of DNA damage and repair upon the risk of treatment related leukemia.Effect of nitric oxide on the anticancer activity of the topoisomerase-active drugs etoposide and adriamycin in human melanoma cells.Therapy-related myelodysplasia and acute myeloid leukemia Topoisomerase II and leukemia.Phytochemicals as Anticancer and Chemopreventive Topoisomerase II Poisons.Etoposide quinone is a covalent poison of human topoisomerase IIβ.Simultaneous determination of etoposide and its catechol metabolite in the plasma of pediatric patients by liquid chromatography/tandem mass spectrometry.Preferential induction of MLL(Mixed Lineage Leukemia) rearrangements in human lymphocyte cultures treated with etoposide.Etoposide pathway.Effects of topoisomerase 2 inhibitors on the MLL gene in children receiving chemotherapy: a prospective study.Clustering of genomic breakpoints at the MLL locus in therapy-related acute leukemia with t(4;11)(q21;q23).

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P2860

Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.

http://www.wikidata.org/entity/Q31914935

description

2001 nî lūn-bûn

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2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի փետրվարին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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Etoposide metabolites enhance ...... MLL translocation breakpoints.

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Etoposide metabolites enhance ...... MLL translocation breakpoints.

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Etoposide metabolites enhance ...... MLL translocation breakpoints.

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Etoposide metabolites enhance ...... MLL translocation breakpoints.

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Blair IA

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Burden DA

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10.1021/BI002361X

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