Regulation of RasGRP via a phorbol ester-responsive C1 domain. - Wikidata - awgldk - TriplyDB

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

http://www.wikidata.org/entity/Q31973953

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Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3 Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia Direct demonstration of involvement of protein kinase Calpha in the Ca2+-induced platelet aggregation Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1 Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptor Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol esters The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties Diacylglycerol kinase zeta regulates Ras activation by a novel mechanism RasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responses The role and regulation of mTOR in T-lymphocyte function Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?The Immunomodulatory Functions of Diacylglycerol Kinase ζ Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta LAT, the linker for activation of T cells: a bridge between T cell-specific and general signaling pathways The neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57BL/6 mice Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats RasGRP is essential for mouse thymocyte differentiation and TCR signaling Ras history: The saga continues.Identification of a Ras GTPase-activating protein regulated by receptor-mediated Ca2+ oscillations.Identification and characterization of an activating TrkA deletion mutation in acute myeloid leukemia.Regulation of RasGRP1 function in T cell development and activation by its unique tail domain.Sites of phosphorylation by protein kinase A in CDC25Mm/GRF1, a guanine nucleotide exchange factor for Ras.The use of knockout mice reveals a synergistic role of the Vav1 and Rasgrf2 gene deficiencies in lymphomagenesis and metastasis Hyperactive Ras as a therapeutic target in neurofibromatosis type 1.Amphitropic proteins: regulation by reversible membrane interactions (review).The frequencies of calcium oscillations are optimized for efficient calcium-mediated activation of Ras and the ERK/MAPK cascade.The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling.Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters.The Gab1 docking protein links the b cell antigen receptor to the phosphatidylinositol 3-kinase/Akt signaling pathway and to the SHP2 tyrosine phosphatase.Diacylglycerol kinase ζ limits B cell antigen receptor-dependent activation of ERK signaling to inhibit early antibody responses Zap-70-independent Ca(2+) mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation.RasGRP3 contributes to formation and maintenance of the prostate cancer phenotype.Diacylglycerols containing Omega 3 and Omega 6 fatty acids bind to RasGRP and modulate MAP kinase activation.Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.Membrane targeting by C1 and C2 domains.Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.

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P2860

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

http://www.wikidata.org/entity/Q31973953

description

1998 nî lūn-bûn

@nan

1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

@ast

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

@en

type

label

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

@ast

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

@en

prefLabel

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

@ast

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

@en

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Molecular and Cellular Biology

P1476

Regulation of RasGRP via a phorbol ester-responsive C1 domain

@en

P2093

C E Tognon

http://www.w3.org/2001/XMLSchema#string

C J Der

http://www.w3.org/2001/XMLSchema#string

H E Kirk

http://www.w3.org/2001/XMLSchema#string

I P Whitehead

http://www.w3.org/2001/XMLSchema#string

R J Kay

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

N terminus of Sos1 Ras exchange factor: critical roles for the Dbl and pleckstrin homology domains

Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase

Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

Expression of Thy-1 on human hematopoietic progenitor cells

Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

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6995-7008

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10.1128/MCB.18.12.6995

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12

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Lori Anne Passmore

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13468079

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9819387

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109282

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