Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters. - Wikidata - awgldk - TriplyDB

Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters.

Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters.

http://www.wikidata.org/entity/Q33924084

about

RasGRP4 is a novel Ras activator isolated from acute myeloid leukemia Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of beta2-chimaerin, a 'non-protein kinase C' phorbol ester receptor Chimaerins, novel non-protein kinase C phorbol ester receptors, associate with Tmp21-I (p23): evidence for a novel anchoring mechanism involving the chimaerin C1 domain Phorbol esters and related analogs regulate the subcellular localization of beta 2-chimaerin, a non-protein kinase C phorbol ester receptor LAT, the linker for activation of T cells: a bridge between T cell-specific and general signaling pathways Phosphorylation of NG2 proteoglycan by protein kinase C-alpha regulates polarized membrane distribution and cell motility Diacylglycerol-stimulated endocytosis of transferrin in trypanosomatids is dependent on tyrosine kinase activity Protein kinase C alpha signaling inhibits cyclin D1 translation in intestinal epithelial cells Differential actin isoform reorganization in the contracting A7r5 cell Diacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signaling Activation of NFAT-dependent gene expression by Nef: conservation among divergent Nef alleles, dependence on SH3 binding and membrane association, and cooperation with protein kinase C-theta A diacylglycerol-dependent signaling pathway contributes to regulation of antibacterial autophagy.Protein kinases C translocation responses to low concentrations of arachidonic acid.Induction of ANGPTL4 expression in human airway smooth muscle cells by PMA through activation of PKC and MAPK pathways.Bryostatin analogue-induced apoptosis in mantle cell lymphoma cell lines Zap-70-independent Ca(2+) mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation.Increased membrane affinity of the C1 domain of protein kinase Cdelta compensates for the lack of involvement of its C2 domain in membrane recruitment RACK1 mediates activation of JNK by protein kinase C [corrected].Sensitization of human pancreatic cancer cells harboring mutated K-ras to apoptosis Involvement of B-50 (GAP-43) phosphorylation in the modulation of transmitter release by protein kinase C.The complex and intriguing lives of PIP2 with ion channels and transporters.Genetic ablation of PKC epsilon inhibits prostate cancer development and metastasis in transgenic mouse model of prostate adenocarcinoma Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm Lipid phosphatases in the regulation of T cell activation: living up to their PTEN-tial.Topically applied Hsp90 inhibitor 17AAG inhibits UVR-induced cutaneous squamous cell carcinomas Control of protein kinase C activity, phorbol ester-induced cytoskeletal remodeling, and cell survival signals by the scaffolding protein SSeCKS/GRAVIN/AKAP12.Rac signaling in breast cancer: a tale of GEFs and GAPs.The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling.DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signaling Role of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling.Constitutive activation of STAT3 in breast cancer cells: A review.Characterization of cellular DGK-theta Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals.Tissue-specific conditional PKCε knockout mice: a model to precisely reveal PKCε functional role in initiation, promotion and progression of cancer.Biochemical characterization of hyperactive beta2-chimaerin mutants revealed an enhanced exposure of C1 and Rac-GAP domains.Regulation of cardiac excitability by protein kinase C isozymes.Specifying protein kinase C functions in melanoma.High-throughput screening identifies compounds that enhance lentiviral transduction.Protein kinase C in cancer: The top five unanswered questions.Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor.

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P2860

Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters.

http://www.wikidata.org/entity/Q33924084

description

2000 nî lūn-bûn

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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2000 թվականի մայիսին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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Eyes wide shut: protein kinase ...... phorbol ester tumor promoters.

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Eyes wide shut: protein kinase ...... phorbol ester tumor promoters.

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Eyes wide shut: protein kinase ...... phorbol ester tumor promoters.

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Eyes wide shut: protein kinase ...... phorbol ester tumor promoters.

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Eyes wide shut: protein kinase ...... phorbol ester tumor promoters.

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Eyes wide shut: protein kinase ...... phorbol ester tumor promoters.

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Molecular Carcinogenesis

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Eyes wide shut: protein kinase ...... phorbol ester tumor promoters.

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Kazanietz MG

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P2860

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

Human munc13 is a diacylglycerol receptor that induces apoptosis and may contribute to renal cell injury in hyperglycemia

Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testes

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

Bcr encodes a GTPase-activating protein for p21rac

The extended protein kinase C superfamily

Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence

The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia

beta2-chimaerin is a novel target for diacylglycerol: binding properties and changes in subcellular localization mediated by ligand binding to its C1 domain

Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester

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